Results 161 to 170 of about 2,307,247 (300)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Intensity modulation of frequency-specific optoacoustic stimulation at the peripheral hearing level. [PDF]

Z Med Phys
Dries P, Lim HH, Hinsberger M, Sorg K, Pillong L, Langenbucher A, Schick B, Wenzel GI.   +7 more
europepmc   +1 more source

Ultra-Sensitive Fiber Refractive Index Sensor with Intensity Modulation and Self-Temperature Compensation. [PDF]

Sensors (Basel), 2019
Li Z, Hou L, Ran L, Kang J, Yang J.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Personalized intensity modulation radiation therapy auto-planning for esophageal cancer. [PDF]

Sci Rep
Lin CY, Shiau AC, Wang YC, Kuo YC, Wang TH, Hsu SM.   +5 more
europepmc   +1 more source

Use of artificial neural network for pretreatment verification of intensity modulation radiation therapy fields. [PDF]

Br J Radiol, 2019
Mahdavi SR, Tavakol A, Sanei M, Molana SH, Arbabi F, Rostami A, Barimani S.   +6 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Cross-domain correspondence intensity modulation based on Bayesian-decision for remote sensing image pansharpening. [PDF]

PLoS One
Wu L, Jiang X, Zhao Z, Xu Z, Liu J.
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Intensity Modulation Effects on Ultrafast Laser Ablation Efficiency and Defect Formation in Fused Silica. [PDF]

Nanomaterials (Basel)
Yoshitomi D, Takada H, Kinugasa S, Ogawa H, Kobayashi Y, Narazaki A.   +5 more
europepmc   +1 more source