Results 81 to 90 of about 349,914 (309)

High-speed operation of optical exclusive OR circuit based on balanced detection and intensity modulation

open access: yesThe Journal of Engineering, 2015
We report the evaluated results of an optical exclusive OR (XOR) circuit for high-speed binary signals, which operates based on balanced detection and intensity modulation.
Koichi Takiguchi
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Solid-Electrolyte-Gated Graphene-Covered Metal-Insulator-Silicon-Insulator-Metal Waveguide With a Remarkably Large Modulation Depth

open access: yesIEEE Access, 2019
Silicon photonic modulators are an essential element in providing fast and massive connectivity to the data-centric world. Ever-increasing data usage requires them to be smaller, faster, and easier to fabricate.
Yonghan Kim, Min-Suk Kwon
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Low-Cost Sensing with Plastic Optical Fibers—From Turbidity and Refractive Index to Chemical Sensing

open access: yesProceedings, 2019
This manuscript presents low-cost sensing systems for the monitoring of liquids, namely water and beverages quality assessment, with remote and in-site monitoring capabilities.
Filipa Sequeira   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

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