Results 51 to 60 of about 1,266,920 (349)

Body weight definitions for evaluating a urinary diagnosis of acute kidney injury in patients with sepsis

open access: yesBMC Nephrology, 2018
Background We hypothesized that the use of actual body weight might lead to more frequent misdiagnosis of acute kidney injury (AKI) than when ideal body weight is used in underweight and/or obese patients.
Shinshu Katayama   +7 more
doaj   +1 more source

Direct discharge from the intensive care unit improved patient flow in a resource-pressured health system

open access: yesJournal of Anesthesia, Analgesia and Critical Care, 2023
Critical care practice is constantly evolving. Pressures for bed availability in publicly funded healthcare systems have led to an increase in patients delayed in their discharge from critical care to the wards.
E. O’Riordan   +3 more
doaj   +1 more source

Narrative Medicine In Intensive Care

open access: yesAnesthesia & Clinical Care, 2019
Narrative Medicine fortifies clinical practice with the narrative competence to interpret the stories of illness. The histories of illness pass through a process of listening and empathic understanding aimed at the therapeutic objective. Storytelling is an inherent behavior in humans. This becomes more important in intensive care where technology often
E. Primerano, D. Alampi
openaire   +2 more sources

Recommendations for core critical care ultrasound competencies as a part of specialist training in multidisciplinary intensive care: a framework proposed by the European Society of Intensive Care Medicine (ESICM)

open access: yesCritical Care, 2020
Critical care ultrasound (CCUS) is an essential component of intensive care practice. Although existing international guidelines have focused on training principles and determining competency in CCUS, few countries have managed to operationalize this ...
Adrian Wong   +30 more
semanticscholar   +1 more source

The use of automated pupillometry to assess cerebral autoregulation: a retrospective study

open access: yesJournal of Intensive Care, 2020
Background Critically ill patients are at high risk of developing neurological complications. Among all the potential aetiologies, brain hypoperfusion has been advocated as one of the potential mechanisms.
Armin Quispe Cornejo   +7 more
doaj   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Optimization of the treatment with beta-lactam antibiotics in critically ill patients—guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique—SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d’

open access: yesCritical Care, 2019
BackgroundBeta-lactam antibiotics (βLA) are the most commonly used antibiotics in the intensive care unit (ICU). ICU patients present many pathophysiological features that cause pharmacokinetic (PK) and pharmacodynamic (PD) specificities, leading to the ...
R. Guilhaumou   +12 more
semanticscholar   +1 more source

Carbon monoxide in intensive care medicine—time to start the therapeutic application?!

open access: yesIntensive Care Medicine Experimental, 2020
Carbon monoxide (CO) is not only known as a toxic gas due to its characteristics as an odorless molecule and its rapid binding to haem-containing molecules, thus inhibiting the respiratory chain in cells resulting in hypoxia.
U. Goebel, Jakob Wollborn
semanticscholar   +1 more source

Predicting the occurrence of multidrug-resistant organism colonization or infection in ICU patients: development and validation of a novel multivariate prediction model

open access: yesAntimicrobial Resistance and Infection Control, 2020
Background Multidrug-resistant organisms (MDROs) have emerged as an important cause of poor prognoses of patients in the intensive care unit (ICU). This study aimed to establish an easy-to-use nomogram for predicting the occurrence of MDRO colonization ...
Li Wang   +11 more
doaj   +1 more source

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