Results 41 to 50 of about 314,392 (318)

The impact of postoperative fluid balance on early hepatic function and renal replacement therapy requirement after liver transplantation: a single-center retrospective cohort study

open access: yesEuropean Journal of Medical Research
Objective Liver transplantation (LT) is the definitive treatment for end-stage liver disease, with acute kidney injury (AKI) and renal replacement therapy (RRT) as common severe early complications.
Shenghai Tan   +5 more
doaj   +1 more source

Epidemiology of bloodstream infections and antimicrobial susceptibility pattern in ICU and non-ICU wards: A four-year retrospective study in Isfahan, Iran

open access: yesAdvanced Biomedical Research, 2023
Background: Bloodstream infections (BSIs) are one of the causes of morbidity and mortality in hospitalised patients. This study evaluated BSI's incidence, trend, antimicrobial susceptibility patterns and mortality in AL Zahra Hospital in Isfahan, Iran ...
Nazila Kassaian   +5 more
doaj   +1 more source

Predictors of compassion satisfaction among healthcare professionals working in intensive care units: A cross-sectional study

open access: yes, 2023
Objective: To determine the prevalence of compassion satisfaction, related factors, and predictors among healthcare professionals in Thai intensive care units.
Amy E. Mitchell   +7 more
core   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi   +6 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Offline Safe Reinforcement Learning for Sepsis Treatment: Tackling Variable-Length Episodes with Sparse Rewards

open access: yesHuman-Centric Intelligent Systems
In critical medicine, data-driven methods that assist in physician decisions often require accurate responses and controllable safety risks. Most recent reinforcement learning models developed for clinical research typically use fixed-length and very ...
Rui Tu   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Characteristics and outcomes of patients admitted to the first psychiatric intensive care unit in Egypt

open access: yesSouth African Journal of Psychiatry, 2021
Background: Psychiatric intensive care units (PICU) have become an essential part of psychiatric hospital design worldwide, there are few published data about their effectiveness.
Tarek A. Okasha   +4 more
doaj   +1 more source

Scoping review of animal assisted activities in intensive care units

open access: yes, 2022
Introduction: Research in acute care settings has shown that animal assisted activities (AAA) have the capacity to benefit both patients and staff. There is substantial anecdotal evidence of AAA being used in intensive care environments however, there is
Lovell, Tania, Ranse, Kristen
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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