Results 101 to 110 of about 3,283,391 (348)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Developing Students’ Reading Culture for Academic Reading Level through Metacognitive Strategies

open access: yesLingua Cultura, 2018
The development of reading culture for this academic level used the metacognitive strategies. This research was a case study in wihich the data sources were randomly drawn from various print sources by cutting off the core of the text to be analyzed. The
Pranowo pranowo
doaj   +1 more source

EXTENSIVE AND INTENSIVE READING APPROACHES IN TEACHING ENGLISH READING

open access: yesALENA : Journal of Elementary Education, 2023
Artikel ini menjelaskan dasar konseptual dari pendekatan membaca ekstensif dan intensif dalam pengajaran membaca bahasa Inggris. Uraian dan ilustrasi tersebut berasal dari berbagai sumber, pengalaman, dan referensi. Pembahasan topik didasarkan pada hasil interpretasi dan kajian teoritis, yang kemudian dipadukan dengan hasil penelitian dan observasi ...
openaire   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

The Impact of Using Inverted Classrooms on Promoting Extensive versus Intensive Reading Comprehension among Iranian Upper-intermediate EFL Learners

open access: yes, 2019
This study aimed to investigate the impact of inverted classrooms on promoting Iranian EFL learners’ extensive and intensive reading comprehension. To fulfil, 60 Iranian upper-intermediate EFL students out of 90 were chosen based on an Oxford Quick ...
L. Neisi   +2 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

The Development of Character-Based Intensive Reading Text Book in Elementary School

open access: yesJurnal Pendidikan Humaniora, 2015
Pengembangan Buku Teks Membaca Intensif Berbasis Karakter di Sekolah Dasar Abstract: The purpose of this study was (1) to develop instructional materials intensive reading of literary and non-literary class VI character-based, including materials and ...
Wisda Miftakhul Ulum
doaj   +1 more source

Vowel intensity in read Japanese.

open access: yesJournal of the Acoustical Society of Japan (E), 1994
The peak intensity values of vowels in several CV moras were studied, using a passage of news-broadcasting read by a professional male speaker. Several factors operate in determining vowel intensity.(1) Grammatical function of the word in which the vowel is located: the most significant and consistent difference is higher intensities for nouns than ...
Noriko Umeda   +3 more
openaire   +2 more sources

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