Results 81 to 90 of about 819,191 (294)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

PENGARUH MODEL PEMBELAJARAN COOPERATIVE INTEGRATED READING AND COMPOSITION TERHADAP KEMAMPUAN MEMBACA INTENSIF [PDF]

, 2013
: The aim of this research was to find out the differences of intensive reading ability between student who taught by Cooperative Integrated Reading and Composition learning model and direct instruction learning model.
Amir,, Riyadi,, Utami, Galis
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Vowel intensity in read Japanese.

Journal of the Acoustical Society of Japan (E), 1994
The peak intensity values of vowels in several CV moras were studied, using a passage of news-broadcasting read by a professional male speaker. Several factors operate in determining vowel intensity.(1) Grammatical function of the word in which the vowel is located: the most significant and consistent difference is higher intensities for nouns than ...
Noriko Umeda, Yukiko Monzen, Tetsuya Nomura, Hirokazu Sato   +3 more
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A comparison of the impact of extensive and intensive reading approaches on the reading attitudes of secondary EFL learners

Studies in Second Language Learning and Teaching, 2020
Extensive reading (ER) which encourages second or foreign (L2) learners to engage in a great deal of reading, has long been recognized as an efficient approach in L2 reading pedagogy.
A Young Park
doaj  

PENINGKATAN KETERAMPILAN MEMBACA INTENSIF MENGGUNAKAN MODEL PEMBELAJARAN KOOPERATIF TIPE CIRC PESERTA DIDIK KELAS IV SDN 01 GEMAWANG, WONOGIRI TAHUN AJARAN 2012/2013 [PDF]

, 2013
Ari Kusuma Rahmawati, PENINGKATAN KETERAMPILAN MEMBACA INTENSIF MENGGUNAKAN MODEL PEMBELAJARAN KOOPERATIF TIPE CIRC PESERTA DIDIK KELAS IV SDN 1 GEMAWANG, WONOGIRI TAHUN AJARAN 2012/2013.
Rahmawati, Ari Kusuma
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Exploring Students' Difficulties in Comprehending Reading for Academic Materials Used in Their Class [PDF]

, 2015
There is a positive correlation between students academic reading skills and their writing skill (Inayah, 2010). This researchexplored students difficulties in comprehending reading for academic materials used in their classroom.
Inayah, R. (Ratih), Rahayu, S. (Silpia)
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source