Results 101 to 110 of about 119,276 (254)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
EXTENSIVE AND INTENSIVE READING APPROACHES IN TEACHING ENGLISH READING
This paper describes the conceptual base of extensive and intensive reading approaches in teaching English reading. The description and illustration come from various sources, experiences, and references.
TAEMBO, MAULID
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Extensive Reading and Graded Readers
This essay is an overview of extensive reading generally, and as it applies to the specific circumstances of Edogawa University. Extensive reading is defi ned and contrasted with intensive reading for second language acquisition.
ハンクス, ジェフ
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Integrated Extensive and Intensive Reading
, 2018 석사학위를 수여받기 위해 제출된 포트폴리오임. 이 논문은 저자가 원문공개에 동의하지 않은 논문으로, 도서관 내에서만 열람이 가능하며, 인쇄 및 저장은 불가합니다.[Introduction] Purpose: To raise learner’s awareness of reading for pleasure Rationale: Extensive reading activities allow leaners to develop their reading ...
최은주
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FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
JISAE (Journal of Indonesian Student Assessment and Evaluation)Effective classroom management is a crucial foundation in the success of learning in Primary School (SD), given the unique characteristics of students at this developmental age.
Bambang Afriadi, Fitri Fitri
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
IMPROVING THE STUDENTS VOCABULARY ACHIEVEMENT THROUGH INTENSIVE READING
, 2015 Tujuan penilitian ini adalah untuk mengetahui apakah ada peningkatan penguasaan kosa kata siswa setelah diajarkan menggunakan teknik intensive reading. Penelitian ini menggunakan pendekatan kuantitatif dan dilaksanakan di kelas X3 yang berjumlah 24 orang.
Sari, Eva Mayang +2 more
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