Results 101 to 110 of about 5,317,329 (303)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Meekatharra, Western Australia [cartographic material].

, 1944
"Drawing and Reproduction L.H.Q. Cartographic Coy., Aust. Survey Corps. April 1944."; Catalogue record generated as part of a batch load.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Mundawindi, Western Australia [cartographic material].

, 1944
"Drawn and Reproduced by L.H.Q. Cartographic Coy. Aust Survey Corps. Feb 1944."; Catalogue record generated as part of a batch load.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Flexible bronchoscopy in the intensive care unit: the FLEXICARE survey

ERJ Open Research
Background Flexible bronchoscopy (FB) is a key diagnostic and therapeutic procedure in the intensive care unit (ICU). However, significant heterogeneity exists regarding indications, peri-procedural management, training and safety practices across ICUs ...
Christoph Fisser, Nina Sicker, Claudia Crimi, Christian Karagiannidis, Joao Carlos Winck, Marieke Duiverman, Ariana Azevedo, Ana Cysneiros, Ignacio Martin-Loeches   +8 more
doaj   +1 more source

Batrachochytrium salamandrivorans (Bsal) not detected in an intensive survey of wild North American amphibians. [PDF]

Sci Rep, 2020
Waddle JH, Grear DA, Mosher BA, Grant EHC, Adams MJ, Backlin AR, Barichivich WJ, Brand AB, Bucciarelli GM, Calhoun DL, Chestnut T, Davenport JM, Dietrich AE, Fisher RN, Glorioso BM, Halstead BJ, Hayes MP, Honeycutt RK, Hossack BR, Kleeman PM, Lemos-Espinal JA, Lorch JM, McCreary B, Muths E, Pearl CA, Richgels KLD, Robinson CW, Roth MF, Rowe JC, Sadinski W, Sigafus BH, Stasiak I, Sweet S, Walls SC, Watkins-Colwell GJ, White CL, Williams LA, Winzeler ME.   +37 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source