Results 121 to 130 of about 5,317,329 (303)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
2008 AdvanceVT Work/Life Survey Questionnaire
, 2008 This survey is being administered in order to help improve the climate for faculty members at Virginia Tech. Aggregate data from the survey will be shared with deans, department heads, and others in order to promote discussion about strategies to help ...
Virginia Tech. Center for Survey Research
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Musgrave, South Australia [cartographic material].
, 1941 1st ed. Relief shown by hachures, form lines and spot heights.; "This map is compiled from the latest Commonwealth and State information and is not the result of precise military survey"; "Printed by A.H.Q.
Australia. Army. Survey Corps.
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
, 1914 Manuscript plane table survey map of Meredith, Geelong and Portarlington regions, Victoria. Relief shown by contours and spot heights.; Title supplied by cataloguer.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Coober Pedy, South Australia [cartographic material].
, 1942 1st ed. Shows telephone and power lines, electric power stations, roads, railways and aerodromes.; Relief shown by hachures, form lines and spot heights.; "This map is compiled from the latest Commonwealth and State information and is not the result of ...
Australia. Army. Survey Corps.
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
2005 AdvanceVT Work/Life Survey Questionnaire
, 2005 Virginia Tech is committed to maintaining a work environment in which all faculty members can succeed. In order to assist the university in achieving this goal, it is important to receive input from all faculty members at the university.
Virginia Tech. Center for Survey Research
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