Results 171 to 180 of about 1,415,466 (305)

Activities and Time Spent on Rehabilitation in Scandinavian ICUs: A Cross-Sectional Survey Among Healthcare Professionals. [PDF]

Acta Anaesthesiol Scand
Alfheim HB, Svenningsen H, Holm A, Ågård AS, Åkerman E, Lind R, Nielsen AH, Collet MO.   +7 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Intraoperative Hypotension and Vasoactive Treatment: An International Survey of Anaesthesiologists. [PDF]

Acta Anaesthesiol Scand
Bækgaard ES, Vester-Andersen M, Crone V, Møller MH, Yamanaka S, Palmarsdottir R, Uusalo P, Haidl F, Rådestad M, van der Sloot K, Corona A, Johnström A, Nørskov AK, Karlsen APH, Faustad BI, Sørensen CB, Spies F, Krogh HB, El-Hallak H, Mistry JM, Mønnich JK, Olesen KG, Madsen KPD, Voogd KL, Reich LM, Kolstrup LA, Juhl-Olsen P, Körner LK, Sigurdsson MI, Jensen-Holm MB, Slavensky JA, Toft MH, Jørgensen ML, Andersen M, Jensen MSH, Saei M, Hedetoft M, Hansen PM, Hansen RT, Lundsgaard RS, Krarup SMI, Wiberg S, Laustrup T, Brizzi G, Kreutziger J, Onyemuchara I, Adeniji A, Colville T, Keitley JA, Khan M, Millar M, Lennie I, Kelly K, Brooker V, Roberts J, Lipton G, Keohone J, Chebbout R, Bond O, Milligan W, O'Brien C, Wright E, Linton F, Towell C, Shuttleworth J, Norton J, Butler D, Frankland S, Screech F, Charig L, Walsh S, Davies R, Jones E, Dalmonte E, Evans M, Krag M.   +75 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Healing Presence: an Intensive Care Unit Curriculum for Medical Students Based on the Clinical Pastoral Education Training Model. [PDF]

Clin Teach
Anderson S, Brazier LJ, Baruch J, Wright C, Collier K.   +4 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Timeframes for "early" mobilisation after abdominal and cardiothoracic surgery: evidence- and consensus-based suggestions of definitions. [PDF]

BMC Surg
Fagevik Olsén M, Sehlin M, Westerdahl E, Svensson-Raskh A, Block L, Engström C, Nygren-Bonnier M, Schandl A.   +7 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Consumer Perspectives on PICU Safety and Quality. [PDF]

Nurs Crit Care
Charles KR, Long DA, Lake A, Hall L, Spotswood NE, Poulter AL, Rahiman S, Gibbons KS, Rickard CM, Schults JA, Australian and New Zealand Intensive Care Society Paediatric Study Group.   +10 more
europepmc   +1 more source

CIHI Survey: Intensive Care in Canada

Healthcare Quarterly, 2006
Kira Leeb, Aleksandra Jokovic, Michaela Sandhu, Greg Zinck   +3 more
openaire   +2 more sources