Results 151 to 160 of about 236,914 (218)

Timeframes for "early" mobilisation after abdominal and cardiothoracic surgery: evidence- and consensus-based suggestions of definitions. [PDF]

BMC Surg
Fagevik Olsén M, Sehlin M, Westerdahl E, Svensson-Raskh A, Block L, Engström C, Nygren-Bonnier M, Schandl A.   +7 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Red blood cell transfusion thresholds in acute leukemia: Current practice and physician perspectives from a national survey. [PDF]

Transfusion
Modi D, Houston BL, Leber B, Jamula E, Heddle N, Hillis C, Zeller MP, Berg T, Arnold DM.   +8 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Infection Control and Prevention Awareness Among Intensive and Cardiac Care Nurses: Implications for Managers and Policymakers. [PDF]

Nurs Open
Alenezi IN, Mersal FA, Aboelola TH.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Post-CICU Recovery Programs: Early Adopters and Care Models. [PDF]

JACC Adv
Nguyen K, Dudzinski DM, Dahiya G, Elliott A, Hillerson DB, Isseh I, Thompson AD, Whiteside HL, Sinha SS.   +8 more
europepmc   +1 more source

Implementation of the FAST HUG if WEAK extended ward round checklist in a tertiary interdisciplinary intensive care unit: a before-and-after quality improvement study. [PDF]

Crit Care Sci
Klar R, Hoffmann A, Blumer J, Cioccari L.   +3 more
europepmc   +1 more source