Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Elucidation of key lactylation- and palmitoylation-related genes and their related mechanisms in the development of neuropathic pain. [PDF]
Yan H, Li L, Li J, Hao J, Yang Y.
europepmc +1 more source
Classroom engagement among undergraduate students at a private college in Qingdao, China: a multidimensional analysis. [PDF]
Yang Z, Lan Y, Liu Q, Chen Q, Sun Y.
europepmc +1 more source
Linking Surface Wettability to Interfacial Thermal Transport at Ti-Water Interfaces: A Molecular Dynamics Study. [PDF]
Huang H +7 more
europepmc +1 more source
Unified Semantic Reasoning and Planning for Autonomous Driving. [PDF]
An YC, Choi JH, Pyo JW, Bae SH, Kuc TY.
europepmc +1 more source
Multi-Mechanistic Effects of Xylopia aethiopica Fruits on Uterine Fibroids: Insights From In Vivo and In Silico Evidence. [PDF]
Oluwasegun A +7 more
europepmc +1 more source
Ozoralizumab, a trivalent anti-TNFα NANOBODY<sup>®</sup> compound, is resistant to rheumatoid factor-mediated modulation of FcRn-dependent recycling and immune complex uptake. [PDF]
Morimoto M +4 more
europepmc +1 more source

