Interpersonal confidence as a factor in the prevention of disorganized interaction [PDF]
Human communities are based on a certain set of everyday attitudes, on the coordination of the actions of “the self ” in a group, and on the regulation of social practices.
Dontsov, Aleksander I. +1 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Interaction with disabled persons scale: Factor structure verification [PDF]
Examining attitudes towards people with disabilities has been a field of interest of numerous authors in recent years. Accordingly, different scales for measuring attitudes have been used, both at social and personal level.
Bakoč Andrijana +3 more
doaj
Trust as a factor of psychological security in interethnic interaction
The direction and role of trust as a factor of psychological security in social interac- tion is the subject of research attention of Russian and foreign scientists.
Dontsov A.I. +3 more
doaj +1 more source
TGFBR1 intralocus epistatic interaction as a risk factor for colorectal cancer. [PDF]
In colorectal cancer (CRC), an inherited susceptibility risk affects about 35% of patients, whereas high-penetrance germline mutations account for
Ana Martinez-Canto +15 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Distinct Mechanisms for Induction and Tolerance Regulate the Immediate Early Genes Encoding Interleukin 1β and Tumor Necrosis Factor α [PDF]
Interleukin-1β and Tumor Necrosis Factor α play related, but distinct, roles in immunity and disease. Our study revealed major mechanistic distinctions in the Toll-like receptor (TLR) signaling-dependent induction for the rapidly expressed genes (IL1B ...
Unlu, Sebnem +49 more
core +1 more source
Connective tissue growth factor (CTGF/CCN2) is negatively regulated during neuron-glioblastoma interaction. [PDF]
Connective-tissue growth factor (CTGF/CCN2) is a matricellular-secreted protein involved in complex processes such as wound healing, angiogenesis, fibrosis and metastasis, in the regulation of cell proliferation, migration and extracellular matrix ...
Luciana F Romão +7 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

