Results 61 to 70 of about 9,563,918 (311)

Reflection 6 [PDF]

open access: yes, 2010
The 2nd International Academic Forum for the Next Generation, The 4th ICIS International Forum, The 3rd ICIS International Symposium, Korean Studies Advancement Center and ICIS Cosponsored International Symposium, Some Thoughts on Bōnotsu, Conversation ...
4750   +1 more
core  

Interaction of complement factor h and fibulin3 in age-related macular degeneration. [PDF]

open access: yesPLoS ONE, 2013
Age-related macular degeneration (AMD) is a major cause of vision loss. It is associated with development of characteristic plaque-like deposits (soft drusen) in Bruch's membrane basal to the retinal pigment epithelium (RPE).
M Keith Wyatt   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Analysis of the interaction of TIP60β and PIN1 with the ets family transcription factor ETV6 [PDF]

open access: yes, 2005
The ETV6 gene is involved in many chromosomal translocations forming different fusion genes in both myeloid and lymphoid leukemias as well as in some solid tumors.
Zhang, Chang-Dong
core   +1 more source

Connective tissue growth factor (CTGF/CCN2) is negatively regulated during neuron-glioblastoma interaction. [PDF]

open access: yesPLoS ONE, 2013
Connective-tissue growth factor (CTGF/CCN2) is a matricellular-secreted protein involved in complex processes such as wound healing, angiogenesis, fibrosis and metastasis, in the regulation of cell proliferation, migration and extracellular matrix ...
Luciana F Romão   +7 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Virtual environment-based teleoperation of forestry machines : designing future interaction methods [PDF]

open access: yes, 2013
Virtual environment-assisted teleoperation has great potential as a human-robot interaction paradigm for field robotic systems, in particular when combined with elements of automation. Unstructured outdoor environments present a complex problem with many
Westerberg, Simon   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Reflection 7 [PDF]

open access: yes, 2011
The Report on Fieldwork in Amakusa, The 5th ICIS International Workshop, The 4th International Symposium, International Academic Symposium, Cultural Interaction Studies on Food (6), Activities and Announcements, Solicitation of Submissions for the ...
Institute, For Cultural Interaction Studies Kansai University   +1 more
core  

Proteolytic interactions of factor IXa with human factor VIII and factor VIIIa [PDF]

open access: yesBlood, 1992
Abstract Factor IXa was shown to inactivate both factor VIII and factor VIIIa in a phospholipid-dependent reaction that could be blocked by an antifactor IX antibody. Factor IXa-catalyzed inactivation correlated with proteolytic cleavages within the A1 subunit of factor VIIIa and within the heavy chain (contiguous A1-A2-B domains) of ...
B J, Lamphear, P J, Fay
openaire   +3 more sources

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