Results 51 to 60 of about 9,563,918 (311)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reflection 5 [PDF]

open access: yes, 2010
Society for Cultural Interaction in East Asia, The 1st General Assembly and 1st Annual Meeting 2009 New Approaches to Multicultural Interaction, Column 1: Who Owns World Heritage?– An Attempt for Sharing Historical Understanding, ICIS Periphery Project ...
Institute, for Cultural Interaction Studies Kansai University   +2 more
core  

Interaction with disabled persons scale: Factor structure verification [PDF]

open access: yesSpecijalna Edukacija i Rehabilitacija, 2018
Examining attitudes towards people with disabilities has been a field of interest of numerous authors in recent years. Accordingly, different scales for measuring attitudes have been used, both at social and personal level.
Bakoč Andrijana   +3 more
doaj  

Trust as a factor of psychological security in interethnic interaction

open access: yesСоциальная психология и общество, 2018
The direction and role of trust as a factor of psychological security in social interac- tion is the subject of research attention of Russian and foreign scientists.
Dontsov A.I.   +3 more
doaj   +1 more source

Interpersonal confidence as a factor in the prevention of disorganized interaction [PDF]

open access: yesPsychology in Russia: State of Art, 2014
Human communities are based on a certain set of everyday attitudes, on the coordination of the actions of “the self ” in a group, and on the regulation of social practices.
Dontsov, Aleksander I.   +1 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

TGFBR1 intralocus epistatic interaction as a risk factor for colorectal cancer. [PDF]

open access: yesPLoS ONE, 2012
In colorectal cancer (CRC), an inherited susceptibility risk affects about 35% of patients, whereas high-penetrance germline mutations account for
Ana Martinez-Canto   +15 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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