Results 81 to 90 of about 47,986 (308)
An interactional sociolinguistic study of fictional characters' conversational exchanges / [PDF]
, 1999 Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e ...
Mesquita, Claudia
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Computations and Interaction [PDF]
, 2011 We enhance the notion of a computation of the classical theory of computing with the notion of interaction. In this way, we enhance a Turing machine as a model of computation to a Reactive Turing Machine that is an abstract model of a computer as it is used nowadays, always interacting with the user and the world.
J.C.M. Baeten (Jos) +2 more
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Humanities & Social Sciences CommunicationsYe “also/too/as well” is one of the most frequently used adverbs in Mandarin Chinese. Although the lexical meaning and syntactic properties of ye have been widely discussed, there are few analyses of ye expressions in interactional discourse, let alone ...
Lu Xue, Shuangyun Yao
doaj +1 more source
Frontiers in EducationThis mixed-method experimental study investigates the effectiveness and typology of interactional feedback in supporting digital game-based language learning, focusing on two groups of primary language teachers.
Abdulmajeed Alghamdi
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
INTERACTIONAL JUSTICE: THE LINK BETWEEN EMPLOYEE RETENTION AND EMPLOYMENT LAWSUITS [PDF]
Organizational justice is one of the least understood and underutilized tools to create a better and more effective workplace. In this article, we’ll focus on interactional justice, look at its impact, and offer strategies for creating a climate that ...
Raluca Cruceru, Cristina Macarescu
core
Calidoscópio, 2017 This paper analyses the interactional positionings negotiated by a migrant student in the context of a situated narrative interview. This investigation takes into account the performative nature of language and the performative theorization of narratives.
Letícia Fonseca Richthofen de Freitas +1 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source