Results 51 to 60 of about 88,914 (262)
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Patients with head and neck cancer report high unmet psychosocial needs as they undergo lifesaving treatments that can significantly alter their appearance and cause functional impairments.
Maria Cherba +9 more
doaj +1 more source
The Second Language Classroom Modes by Senior English Teacher at XYZ English Course in Surabaya [PDF]
This study is intended to find out the pedagogic goals, interactional features, and L2 classroom modes appeared in the fourth graders' English classroom taught by senior English teacher.
Wijaya, H. P. (Henny) +1 more
core
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Tense situations and the significance of stability for psychological security [PDF]
Present reality gives rise to contradictory trends: the combination of new threats, tense situations, and destructive tendencies shapes awareness of the importance of identifying, assessing, and managing emerging situations and of developing new ...
Dontsov, Aleksander I. +1 more
doaj +1 more source
Women’s leadership as narrative practice: identifying ‘tent making’, ‘dancing’ and ‘orchestrating’ in UK Early Years Services [PDF]
Purpose – The paper discusses the “narrative practices” utilised by women leading in a small sample of Early Years services in the North East of England.
Ian Robson, Sharon Mavin
core +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Culture as Non-Consensus: Exploring Coherence Among Native Speakers’ Perceptions of German Expressions of Affection [PDF]
From early in their learning experience, foreign language (FL) learners at American universities explore socio-cultural connotations that, it is argued, are signified by FL words.
Fichtner, Friederike
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source

