Results 241 to 250 of about 16,557,675 (399)

Host-Gut Microbiota Metabolic Interactions

Science, 2012
J. Nicholson, E. Holmes, J. Kinross, R. Burcelin, G. Gibson, W. Jia, S. Pettersson   +6 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Plant-Pollinator Interaction Rewiring Boosts Year-to-Year Community Persistence. [PDF]

Ecol Lett
Domínguez-Garcia V, Molina FP, Allen-Perkins A, Godoy O, Bartomeus I.   +4 more
europepmc   +1 more source

Helical structures in layered magnetic superconductors due to indirect exchange interactions mediated by interlayer tunneling [PDF]

, 2019
A. E. Koshelev
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Online native hydrophobic interaction chromatography-mass spectrometry of antibody-drug conjugates

Trevor Kempen, Lance Cadang, Yuchen Fan, Kelly Zhang, Tao Chen, Bingchuan Wei   +5 more
openalex   +1 more source

Minireview: Protein Interactions [PDF]

, 2012
Child, Jessica
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Specific interactions between fluorinated vitamin-D₃ derivatives and vitamin-D receptor: molecular mechanics and ab initio fragment molecular orbital calculations. [PDF]

J Mol Model
Yuguchi M, Takenaka S, Nakatani C, Nagura Y, Sabishiro H, Chimura N, Kittaka A, Takimoto-Kamimura M, Kurita N.   +8 more
europepmc   +1 more source

On the consistency of a non-Hermitian Yukawa interaction

, 2020
Jean Alexandre, Nick E. Mavromatos
openalex   +1 more source