Results 91 to 100 of about 305,447 (272)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Development of Accounting Learning E-Modules with a Guided Inquiry Approach to Increase Student Learning Motivation in Accounting Computer Subjects

open access: yesTarbiyah: Jurnal Ilmiah Kependidikan
The application of the guided inquiry model is an alternative to increase student involvement during the learning process. This research aims to produce a learning E-module. The implication is that the guided inquiry-based accounting E-Module effectively
Adrianus Junaidi Subari   +1 more
doaj   +1 more source

Comparing the effectiveness of asynchronous e-modules and didactic lectures to teach electrocardiogram interpretation to first year US medical students

open access: yesBMC Medical Education, 2023
Background Medical students are expected to be competent in interpreting electrocardiograms (ECGs) by the time they graduate, but many are unable to master this skill.
Doreen M. Olvet, Kaveh Sadigh
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Pengembangan E-Modul Kontekstual Interaktif Berbasis Web pada Mata Pelajaran Kimia Senyawa Hidrokarbon

open access: yesMultitek Indonesia, 2018
Supporting the implementation of effective learning process, can not be separated from the use of teaching materials that is module. Modules are also developed in electronic form / format called emodules E-module Is an interactive module that displays ...
Yulia Nalarita, Tomi Listiawan
doaj   +1 more source

WORKSHOP: CREATE AN E-MODULE INTERACTIVE WITH EBOOK CREATOR APLICATION

open access: yesKhidmatuna: Jurnal Pengabdian Masyarakat
The Covid-19 pandemic has had a huge impact, such as many schools in the world being closed to stop the spread of Covid-19. The impact of the Covid-19 pandemic has made the government create an online learning program. Online or online learning is learning based on digital media technology in which learning materials are sent electronically or in the ...
null Tuti Marlina   +1 more
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Shape: A 3D Modeling Tool for Astrophysics

open access: yes, 2010
We present a flexible interactive 3D morpho-kinematical modeling application for astrophysics. Compared to other systems, our application reduces the restrictions on the physical assumptions, data type and amount that is required for a reconstruction of ...
Koning, Nicholas   +4 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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