Results 101 to 110 of about 1,031,896 (310)
Game Transfer Phenomena and Problematic Interactive Media Use: Dispositional and Media Habit Factors. [PDF]
Front Psychol, 2021 Ortiz de Gortari AB, Gackenbach J.
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The shift to digital: designing for learning from a culturally relevant interactive media perspective. [PDF]
Educ Technol Res Dev, 2021 Engerman JA, Otto RF.
europepmc +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
想像力量表之編製 The Development of an Imagination Scale
Journal of Research in Education Sciences, 2012 本研究目的在發展「想像力量表」，視其信度與效度，全量表共包含13 題開放式題項。研究者透過項目分析、Cronbach’s α、重測信度、個別項目信度、成分信度、組合信度及驗證性因素分析等統計方法來分析處理實證資料。根據驗證性因素分析結果顯示，實證資料尚且支持Vygotsky之想像力概念理論（Vygotsky’s theoretical conceptions of imagination）暨想像力激發機制（the arousing mechanism of imagination）之「想像力量表 ...
曹筱玥 Saiau-Yue Tsau +1 more
doaj +1 more source
INTERACTIVE LEARNING MEDIA DEVELOPMENT ON EDUCATION PNEUMATIC USING MACROMEDIA FLASH 8 CLASS STUDENT XI ELECTRONIC INDUSTRY SKILLS COMPETENCY SMK MUHAMMADIYAH PRAMBANAN [PDF]
, 2012 The purpose of this thesis final project for developing interactive learning media on subjects pneumatic and determine the level of feasibility Developing interactive learning media on subjects pneumatic class student XI Electronic Industry Skills ...
Choirun, Anwar
core
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Serious Games as a Therapeutic Tool in Pediatric Urology: A Review of Current Applications and Future Directions [PDF]
International Neurourology JournalThis paper examines the use of serious games that integrate engaging gameplay with educational and therapeutic benefits with a particular focus on their application in urology.
Hyung Jun Park +2 more
doaj +1 more source