Results 111 to 120 of about 18,037,577 (311)

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Principles of Information Operations

open access: yes, 2004
Interactive Media ElementIW3101Principles of Information ...

core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

CHILDREN'S USE OF INTERACTIVE MEDIA IN EARLY CHILDHOOD - AN EPIDEMIOLOGICAL STUDY. [PDF]

open access: yesRev Paul Pediatr, 2020
Guedes SDC   +5 more
europepmc   +1 more source

Middle East Pictures

open access: yes, 2002
Interactive Media ElementNS4310Middle East ...

core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Master your practice! A quantitative analysis of Device and system handling training to enable competent interactions with intelligent voice assistants

open access: yesComputers in Human Behavior Reports
Intelligent voice assistants (IVAs), such as Siri or Alexa, are voice-based artificial intelligence (AI) systems that help users solve everyday tasks using voice commands.
Maximilian Baumann   +5 more
doaj   +1 more source

Quality of interactive media use in early childhood and child development: a multicriteria analysis. [PDF]

open access: yesJ Pediatr (Rio J), 2020
Nobre JNP   +7 more
europepmc   +1 more source

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