Results 41 to 50 of about 77,977 (254)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Problematic Internet Use in Frontotemporal Dementia: A Case Series
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The present study investigated problematic internet use (PIU) among 61 patients with frontotemporal dementia (FTD) compared to a cohort of 354 patients with mild cognitive impairment (MCI) and Alzheimer's dementia. PIU was identified in 22.9% of FTD patients compared to only 0.8% of AD patients (p < 0.001). Behaviors included compulsive social
Daniele Urso +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Research in Learning TechnologyImmersive virtual reality (VR) and interactive videos represent two forms of interactive multimedia utilized in education. Immersive VR, a relatively recent addition to educational technology, has gained attention with the advent of affordable commercial
Nesreen Haddush, Alec Bodzin
doaj +1 more source
Screendance in the Wake of Screened Dance: Moving Forward Through Interactive Video
The International Journal of Screendance, 2021 This paper argues that screendance has always had a potential for interactivity, looks specifically at interactive video, and tracks its history through video art and video games.
Callum Anderson
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Interactive Video Application: A web-based open-source framework to build interactive videos
SoftwareXThis article introduces Interactive Video Application (IVA), an open source, web-based framework for creating and deploying interactive videos in the cloud. IVA has been designed and developed with modularity and scalability in mind, using a state-of-the-
Santiago Schez-Sobrino +5 more
doaj +1 more source
Video interactions in online video social networks [PDF]
ACM Transactions on Multimedia Computing, Communications, and Applications, 2009 This article characterizes video-based interactions that emerge from YouTube's video response feature, which allows users to discuss themes and to provide reviews for products or places using much richer media than text. Based on crawled data covering a representative subset of videos and users, we present a characterization from two perspectives: the ...
Fabrício Benevenuto +4 more
openaire +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source