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Identification of Type VI Secretion Systems Effector Proteins That Contribute to Interbacterial Competition in Salmonella Dublin [PDF]

open access: yesFrontiers in Microbiology, 2022
The Type VI Secretion System (T6SS) is a multiprotein device that has emerged as an important fitness and virulence factor for many Gram-negative bacteria through the injection of effector proteins into prokaryotic or eukaryotic cells via a contractile ...
Fernando A. Amaya   +7 more
doaj   +9 more sources

A Quorum Sensing-Regulated Type VI Secretion System Containing Multiple Nonredundant VgrG Proteins Is Required for Interbacterial Competition in Chromobacterium violaceum [PDF]

open access: yesMicrobiology Spectrum, 2022
The environmental pathogenic bacterium Chromobacterium violaceum kills Gram-positive bacteria by delivering violacein packed into outer membrane vesicles, but nothing is known about its contact-dependent competition mechanisms.
Júlia A. Alves   +3 more
doaj   +9 more sources

A High-throughput Interbacterial Competition Platform [PDF]

open access: yesBio-Protocol, 2020
Contact-dependent interbacterial competition is a common strategy used by bacteria to fight for their ecological niches. Interbacterial competition is monitored by a competition assay involving co-culturing the attacker and the recipient bacterial cells ...
Hsiao-Han Lin, Erh-Min Lai
doaj   +8 more sources

Bacteriophage Mu contamination impacts interbacterial competition [PDF]

open access: yesInfection and Immunity
Here, we report the identification of bacteriophage Mu contamination in a commonly used Citrobacter rodentium DBS100 ∆cpxRA mutant strain. After re-constructing a new Mu-free ∆cpxRA strain, we independently replicated the results of a recent study by A ...
Kat Pick   +3 more
doaj   +6 more sources

Mutations in Two Paraburkholderia phymatum Type VI Secretion Systems Cause Reduced Fitness in Interbacterial Competition [PDF]

open access: yesFrontiers in Microbiology, 2017
Paraburkholderia phymatum is a highly effective microsymbiont of Mimosa spp. and has also been shown to nodulate papilionoid legumes. P. phymatum was found to be highly competitive both in a natural environment as well as under controlled test conditions
Samanta Bolzan de Campos   +4 more
doaj   +10 more sources

Role of Recipient Susceptibility Factors During Contact-Dependent Interbacterial Competition [PDF]

open access: yesFrontiers in Microbiology, 2020
Bacteria evolved multiple strategies to survive and develop optimal fitness in their ecological niche. They deployed protein secretion systems for robust and efficient delivery of antibacterial toxins into their target cells, therefore inhibiting their ...
Hsiao-Han Lin   +2 more
doaj   +9 more sources

Distinct strategies of diguanylate cyclase domain proteins on inhibition of virulence and interbacterial competition by agrobacteria [PDF]

open access: yesmBio
Diguanylate cyclases (DGCs) synthesize bis-(3′,5′)-cyclic diguanylic acid (c-di-GMP), a critical bacterial second messenger that coordinates diverse biological processes.
Xuan Lai   +3 more
doaj   +6 more sources

A group B streptococcal type VII-secreted LXG toxin mediates interbacterial competition and colonization of the murine female genital tract [PDF]

open access: yesmBio
Group B Streptococcus (GBS) asymptomatically colonizes the vagina but can opportunistically ascend to the uterus and be transmitted vertically during pregnancy, resulting in neonatal pneumonia, bacteremia, and meningitis. GBS is a leading etiologic agent
Alyx M. Job   +2 more
doaj   +6 more sources

Two Type VI Secretion DNase Effectors are Utilized for Interbacterial Competition in the Fish Pathogen Pseudomonas plecoglossicida [PDF]

open access: yesFrontiers in Microbiology, 2022
Pseudomonas plecoglossicida is a facultative fish pathogen that possesses three distinct type VI secretion systems (named T6SS-1, T6SS-2, and T6SS-3). Our previous work indicated that only T6SS-2 of P. plecoglossicida mediates interbacterial competition.
Yanyan Li, Xiaojun Yan, Zhen Tao
doaj   +4 more sources

Genetic characterization of glyoxalase pathway in oral streptococci and its contribution to interbacterial competition [PDF]

open access: yesJournal of Oral Microbiology, 2023
Objectives To analyze contributions to microbial ecology of Reactive Electrophile Species (RES), including methylglyoxal, generated during glycolysis.Methods Genetic analyses were performed on the glyoxalase pathway in Streptococcus mutans (SM) and ...
Lin Zeng   +3 more
doaj   +4 more sources

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