Results 21 to 30 of about 991,295 (131)

The role of proteinaceous toxins secreted by <i>Staphylococcus aureus</i> in interbacterial competition. [PDF]

FEMS Microbes
Abstract Staphylococcus aureus is highly adapted to colonization of the mammalian host. In humans the primary site of colonization is the epithelium of the nasal cavity. A major barrier to colonization is the resident microbiota, which have mechanisms to exclude S. aureus. As such, S.
Garrett SR, Palmer T.
europepmc   +3 more sources

Probiotic living microneedles designed by interbacterial competition for accelerated infected wound healing. [PDF]

Acta Pharm Sin B
Probiotic therapy offers a promising strategy for chronic infected wound management through pathogen suppression and immune modulation. However, its efficacy remains restricted by weak competitiveness in pathogen-rich niches and poor penetration across biofilm barriers.
Wang H, Wu Z, Gao C, Wang W, Chen M, Yuan L, Wang J, Xiao C, Zhou Y, Tong F, Li H, Gao H, Gao X, Fu J.   +13 more
europepmc   +4 more sources

Pesticin-Like Effector VgrG3^cp Targeting Peptidoglycan Delivered by the Type VI Secretion System Contributes to Vibrio cholerae Interbacterial Competition. [PDF]

Microbiol Spectr, 2023
The type VI secretion system used by a broad range of Gram-negative bacteria delivers toxic proteins to target adjacent eukaryotic and prokaryotic cells. Diversification of effector proteins determines the complex bacterium-bacterium interactions and impacts the health of hosts and environmental ecosystems in which bacteria reside.
Liu M, Zhao MY, Wang H, Wang ZH, Wang Z, Liu Y, Li YP, Dong T, Fu Y.   +8 more
europepmc   +4 more sources

Burkholderia cepacia Complex Contact-Dependent Growth Inhibition Systems Mediate Interbacterial Competition. [PDF]

J Bacteriol, 2019
Competition among bacteria affects microbial colonization of environmental niches and host organisms, particularly during polymicrobial infections. The Bcc is a group of environmental bacteria that can cause life-threatening opportunistic infections in patients who have cystic fibrosis or are immunocompromised. Understanding the mechanisms
Myers-Morales T, Oates AE, Byrd MS, Garcia EC.   +3 more
europepmc   +4 more sources

Shigella sonnei Encodes a Functional T6SS Used for Interbacterial Competition and Niche Occupancy [PDF]

Cell Host and Microbe, 2017
Shigella is a leading cause of dysentery worldwide, with the majority of infections caused by two subgroups, S. flexneri and S. sonnei. Although S. flexneri has been highly prevalent in low-income countries, global development has brought an increase in S. sonnei at the expense of S. flexneri.
Benoit Marteyn, Philippe Sansonetti, Pascale Vonaesch   +2 more
exaly   +3 more sources

A nonenzymatic effector disrupts <i>Bacteroides</i> cell wall homeostasis via OmpA targeting to mediate interbacterial competition. [PDF]

Proc Natl Acad Sci U S A
The human gut microbiome is a dynamic ecosystem where bacteria engage in interspecies competition using molecular weapons such as the type VI secretion system (T6SS). Here, we characterize BteO–BtiO, a unique effector–immunity pair in Bacteroides fragilis that mediates antagonism via a ...
He J, Chen Z, Jiang K, Yang Y, Li W, Wang X, Xu X, Zheng S, Jiao X, Chen X, Huo L, Lim B, Liu SJ, Gao X.   +13 more
europepmc   +4 more sources

Type VIIb secretion systems in Lactobacillales: insights from streptococci and enterococci [PDF]

Journal of Bacteriology
The type VII secretion system (T7SS) is an ATPase-powered molecular machine encoded by Actinomycetota (T7SSa) and Bacillota (T7SSb) that exports small alpha-helical effectors with functions in interbacterial competition, host colonization, and virulence.
Caitlin S. Wiafe-Kwakye, Abigail E. Glenn, Brady L. Spencer   +2 more
doaj   +2 more sources

T6SS nuclease effectors in Pseudomonas syringae act as potent antimicrobials in interbacterial competition. [PDF]

J Bacteriol
ABSTRACT Type VI secretion system (T6SS) is a potent weapon employed by various Pseudomonas species to compete with neighboring microorganisms for limited nutrients and ecological niches.
Yu X, Yan Y, Zeng J, Liu Y, Sun X, Wang Z, Li L.   +6 more
europepmc   +3 more sources

The SPI-20 and SPI-21 T6SS gene clusters from Salmonella enterica subspecies arizonae encode effector proteins that display antibacterial activity [PDF]

Frontiers in Microbiology
The type VI secretion system (T6SS) is a contact-dependent multiprotein apparatus that contributes to interbacterial competition and pathogenesis in many Gram-negative bacteria.
Ayleen Parra-Calisto, Carlos J. Blondel, Carla Vargas-del Río, Esteban Fernández-Castillo, Felipe Reyes-Méndez, Victoria Soriano-Mora, Andrea Avilés, Viviana Toledo, Fernanda Salazar-Salas, Patricio Espinoza-Jara, Fernando A. Amaya, Carlos A. Santiviago, Juan A. Asenjo, David Pezoa   +13 more
doaj   +2 more sources

The SPI-6 T6SS gene cluster from Salmonella Tennessee encodes a new antibacterial nuclease effector protein [PDF]

Frontiers in Microbiology
The type VI secretion system (T6SS) is a contact-dependent multiprotein apparatus widely distributed in Gram-negative bacteria that contributes to interbacterial competition and pathogenesis via a contractile mechanism.
Carla Vargas-del Río, Jorge Urrea, Ayleen Parra-Calisto, Carlos J. Blondel, Andrea Avilés, Fernanda Salazar-Salas, Patricio Espinoza-Jara, Maira Mora, Dácil Rivera, Fernando A. Amaya, Carlos A. Santiviago, Andrea Moreno-Switt, David Pezoa   +12 more
doaj   +2 more sources