Results 61 to 70 of about 1,371,077 (290)

SYNTHESIS AND ANTINEOPLASTIC ACTIVITY OF CERTAIN TRIAZENE AND TRIAZENO-ACRIDINE COMBILEXIN DERIVATIVES [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2007
Four series of bifunctional ligands have been synthesized as DNA-binding combilexins. These novel agents contain a triazenobenzene sulfonamide linker moiety that is attached to an intercalating acridine or acridone chromophore by a functionalized amide ...
Noha Amin, Nagwa Abdel Gawad, Mohammed Mohammed, Hanan Georgey, Samir Aly   +4 more
doaj   +1 more source

Atomistic Mechanisms Triggered by Joule Heating Effects in Metallic Cu‐Bi Nanowires for Spintronics

Advanced Materials, EarlyView.
Bi doped metallic Cu nanowires are promising for spintronics thanks to the stabilization of a giant spin Hall effect. However, heat resulting from current injection forces Bi to leave solution, forcing segregation into monoatomic decorations which evolve into coherent crystalline aggregates.
Alejandra Guedeja‐Marrón, Juan Ignacio Beltrán, Matilde Saura‐Múzquiz, Paolo Perna, M. Carmen Muñoz, Lucas Pérez, Maria Varela   +6 more
wiley   +1 more source

Binding of DNA-Intercalating Agents to Oxidized and Reduced Quinone Reductase 2

, 2015
Quinone reductase 2 (NQO2) is an enzyme that might have intracellular signaling functions. NQO2 can exist in either an oxidized state or a reduced state, and binding of compounds to one or both of these states inhibits enzymatic activity and could also ...
Brian H. Shilton (496155), Kevin K. K. Leung (1450252)   +1 more
core   +1 more source

Transparent Perovskite Light‐Emitting Diodes with Conductive Oxide Top Electrodes

Advanced Materials, EarlyView.
Transparent perovskite light‐emitting diodes (TrPeLEDs) enable simultaneous display and transparency, expanding application possibilities. Using a metal oxide buffer layer and pulsed laser deposition, TrPeLEDs with diverse compositions and architectures are demonstrated.
Michele Forzatti, Sergio Martínez‐Saiz, Morena Cervino, Edoardo Stanzani, Sandra Jenatsch, Qingsen Zeng, Joo Sung Kim, Dong‐Hyeok Kim, Eojin Yoon, Tae‐Woo Lee, Daniel Tordera, Henk J. Bolink   +11 more
wiley   +1 more source

Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase II. [PDF]

PLoS ONE, 2010
Topoisomerase II is critical for DNA replication, transcription and chromosome segregation and is a well validated target of anti-neoplastic drugs including the anthracyclines and epipodophyllotoxins.
Rachael E Hawtin, David E Stockett, Jo Ann W Byl, Robert S McDowell, Tan Nguyen, Michelle R Arkin, Andrew Conroy, Wenjin Yang, Neil Osheroff, Judith A Fox   +9 more
doaj   +1 more source

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

Advanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj, Roshni Satheesh Babu, Yuxin Xia, Eva Bestelink, Radu Sporea, Nikos Hastas, Ioannis Zeimpekis, Dimitra G. Georgiadou, Sayani Majumdar   +8 more
wiley   +1 more source

Improving the antimicrobial efficacy against resistant Staphylococcus aureus by a combined use of conjugated oligoelectrolytes.

PLoS ONE, 2019
Two membrane-intercalating conjugated oligoelectrolytes (COEs), namely COE-D8 and COE-S6, were combined to achieve enhanced antimicrobial efficacy. COE-D8 has a shorter molecular length than COE-S6 and is typical of effective antimicrobial COE molecules,
Elias L Bazan, Lin Ruan, Cheng Zhou
doaj   +1 more source

Phase Engineering of Nanomaterials (PEN): Evolution, Current Challenges, and Future Opportunities

Advanced Materials, EarlyView.
This review summarizes the synthesis, phase transition, advanced characterization spanning ex situ to in situ and operando techniques, and diverse applications of phase engineering of nanomaterials (PEN). It further outlines key challenges and future opportunities, such as phase stability, architecture control, and artificial intelligence (AI)‐driven ...
Ye Chen, Zhanxi Fan, Jingjie Ge, Qiyuan He, Zhuangchai Lai, Jiawei Liu, Chaoliang Tan, Hua Zhang   +7 more
wiley   +1 more source

Formal Verification of Neural Agents in Non-deterministic Environments [PDF]

, 2020
We introduce a model for agent-environment systems where the agents are implemented via feed-forward ReLU neural networks and the environment is non-deterministic. We study the verification problem of such systems against CTL properties.
Akintunde, Michael E., Lomuscio, Alessio, Kouvaros, Panagiotis, Botoeva, Elena, Akintunde, Michael E   +4 more
core   +1 more source

Recent advances in the synthetic transformation of benzimidazole scaffolds as privileged pharmacophores for cancer chemotherapy (2020–present)

Journal of Saudi Chemical Society
Benzimidazole is a fused heterocycle of benzene and imidazole rings. It has attracted marked attention as a privileged pharmacophore with a wide spectrum of biological activities-bioactivities among which anticancer therapeutic potential is most studied.
Ali Irfan, Mahwish Arshad, Sami A. Al-Hussain, Ayesha Amin, Iqra Nasim, Sadaf Ahmad, Bakar Bin Khatab Abbasi, Aamal A. Al-Mutairi, Tahira Khalid, Magdi E. A. Zaki   +9 more
doaj   +1 more source