Results 121 to 130 of about 4,686,959 (289)

Potential role of exosomes derived from the tumor microenvironment in tumor progression and treatment

Frontiers in Oncology
Exosomes are important intercellular communication substances that connect the intercellular communication between the tumor microenvironment and the premetastatic microenvironment during tumor progression.
Ying Yu, Wenjun Zhang, Kun Wang
doaj   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

The role of platelet microvesicles in intercellular communication

Platelets, 2017
In recent years, there has been exponential growth in the interest in microvesicles, which is reflected by the number of publications. Initially referred to as “platelet dust” by Peter Wolf in 1967, platelet microvesicles (PMV) are now recognized as ...
Leonard C. Edelstein
doaj   +1 more source

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Intercellular bridges for cell-cell communication

In multicellular organism, intercellular communication is essential for maintenance of life activity. The intercellular communication includes direct and indirect crosstalk such as gap junction and ligand-receptor interaction, pectively.
Takayuki, Kohno
core  

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Significance of intercellular communication for neurodegenerative diseases

Neural Regeneration Research, 2022
Hilal Cihankaya, Carsten Theiss, Veronika Matschke   +2 more
doaj   +1 more source

Exosomes: mediators of communication in eukaryotes

Biological Research, 2013
In addition to the established mechanisms of intercellular signaling, a new way of communication has gained much attention in the last decade: communication mediated by exosomes.
María A Lopez-Verrilli, Felipe A Court
doaj  

Modulation of intercellular communication between smooth muscle cells by growth factors and cytokines.

, 1996
We recently reported that tumor necrosis factor is able to cause a dose-dependent and persistent reduction in gap junctional intercellular communication between primary human smooth muscle cells.
Geurts, S., Lakemond, C.M.M., Irma Meijerman, Wijk, Th., van der, Thea Van der Wijk, Meijerman, I., Mensink, A., van der Wijk, Th., Catriona M.M. Lakemond, Saskia Geurts, van den Burg, E.H., Erwin H. Van den Burg, Abraham Brouwer, Wim M.F. Jongen, Brouwer, A., Jongen, W.M.F., Burg, E.H., van den, Anne Mensink   +17 more
core   +1 more source