Results 1 to 10 of about 27,252 (136)

Role of tunneling nanotubes in neuroglia [PDF]

Neural Regeneration Research
Tunneling nanotubes are crucial structures for cellular communication and are observed in a variety of cell types. Glial cells, the most abundant cells in the nervous system, play a vital role in intercellular signaling and can show abnormal activation ...
Weichen Xu, Xingyu Yang, Hongmei Zheng, Changzheng Chen, Jiajia Yuan   +4 more
doaj   +2 more sources

Tunneling Nanotubes Facilitate Intercellular Protein Transfer and Cell Networks Function [PDF]

Frontiers in Cell and Developmental Biology, 2022
The past decade witnessed a huge interest in the communication machinery called tunneling nanotubes (TNTs) which is a novel, contact-dependent type of intercellular protein transfer (IPT).
Laura Turos-Korgul, Marta Dorota Kolba, Piotr Chroscicki, Aleksandra Zieminska, Katarzyna Piwocka   +4 more
doaj   +2 more sources

Melatonin, tunneling nanotubes, mesenchymal cells, and tissue regeneration [PDF]

Neural Regeneration Research, 2023
Mesenchymal stem cells are multipotent stem cells that reside in many human tissues and organs. Mesenchymal stem cells are widely used in experimental and clinical regenerative medicine due to their capability to transdifferentiate into various lineages.
Francesca Luchetti, Silvia Carloni, Maria G Nasoni, Russel J Reiter, Walter Balduini   +4 more
doaj   +2 more sources

Chlamydia trachomatis Cell-to-Cell Spread through Tunneling Nanotubes [PDF]

Microbiology Spectrum, 2022
Tunneling nanotubes (TNTs) are transient cellular connections that consist of dynamic membrane protrusions. They play an important role in cell-to-cell communication and mediate the intercellular exchanges of molecules and organelles.
Rico Jahnke, Svea Matthiesen, Luca M. Zaeck, Stefan Finke, Michael R. Knittler   +4 more
doaj   +2 more sources

Inception Mechanisms of Tunneling Nanotubes

Cells, 2019
Tunneling nanotubes (TNTs) are thin membranous tubes that interconnect cells, representing a novel route of cell-to-cell communication and spreading of pathogens. TNTs form between many cell types, yet their inception mechanisms remain elusive. We review
Mitja Drab, David Stopar, Veronika Kralj-Iglic   +2 more
exaly   +3 more sources

A role for tunneling nanotubes in virus spread [PDF]

Frontiers in Microbiology
Tunneling nanotubes (TNTs) are actin-rich intercellular conduits that mediate distant cell-to-cell communication and enable the transfer of various cargos, including proteins, organelles, and virions.
Weimiao Lv, Weimiao Lv, Weimiao Lv, Zichen Li, Zichen Li, Shule Wang, Jingyi He, Leiliang Zhang, Leiliang Zhang, Leiliang Zhang   +9 more
doaj   +2 more sources

HGF/c-Met/β1-integrin signalling axis induces tunneling nanotubes in A549 lung adenocarcinoma cells [PDF]

Life Science Alliance, 2023
Interactions between hepatocyte growth factor (HGF), the c-Met receptor, and β1-integrin induce tunneling nanotubes in A549 cells; paxillin and the downstream MAPK and PI3K pathways and the Arp2/3 complex drive HGF-induced TNT formation.
Griselda Awanis, Salonee Banerjee, Robert Johnson, Sathuwarman Raveenthiraraj, Aya Elmeligy, Derek Warren, Jelena Gavrilovic, Anastasia Sobolewski   +7 more
doaj   +2 more sources

Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators [PDF]

eLife
Tunneling nanotubes (TNTs) are open actin- and membrane-based channels, connecting remote cells and allowing direct transfer of cellular material (e.g. vesicles, mRNAs, protein aggregates) from the cytoplasm to the cytoplasm.
Roberto Notario Manzano, Thibault Chaze, Eric Rubinstein, Esthel Penard, Mariette Matondo, Chiara Zurzolo, Christel Brou   +6 more
doaj   +2 more sources

Mechanical properties of intercellular tunneling nanotubes formed by different mechanisms [PDF]

Heliyon
Tunneling nanotubes (TNTs) that connect cells have been recognized as a pathway for long-range intercellular transport of diverse cargoes, including viruses, lysosomes or other organelles, Ca2+ and electrical signals.
Yanli Sun, Huikai Zhang, Ilya B. Zavodnik, Hucheng Zhao, Xiqiao Feng   +4 more
doaj   +2 more sources

Interplay between tunneling nanotubes and Wnt Signaling: Insights into cytoskeletal regulation and therapeutic potential [PDF]

Biochemistry and Biophysics Reports
Tunneling nanotubes (TNTs) are membranous structures that enable direct intercellular transfer of mitochondria, proteins, RNAs, and signaling molecules, playing key roles in tissue repair, immune coordination, and stress adaptation.
Tengfei Feng, Qi Xu, Shuangshuang Wang, Dongyu Hou, Xunwei Wu   +4 more
doaj   +2 more sources