Multifaceted roles of tunneling nanotubes in intercellular communication [PDF]
Cell-to-cell communication and exchange of materials are vital processes in multicellular organisms during cell development, cell repair and cell survival.
Ludovica eMarzo +2 more
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Mechanical properties of intercellular tunneling nanotubes formed by different mechanisms [PDF]
Tunneling nanotubes (TNTs) that connect cells have been recognized as a pathway for long-range intercellular transport of diverse cargoes, including viruses, lysosomes or other organelles, Ca2+ and electrical signals.
Yanli Sun +4 more
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Tunneling nanotubes provide a new route for bovine viral diarrhea virus spreading [PDF]
IntroductionBovine viral diarrhea virus (BVDV) is one of the major pathogens currently endangering the world's cattle industry. It poses serious difficulties in prevention and treatment because it can infect cattle of all ages and the specific mechanism ...
Jiying Yin +14 more
doaj +2 more sources
Interplay between tunneling nanotubes and Wnt Signaling: Insights into cytoskeletal regulation and therapeutic potential [PDF]
Tunneling nanotubes (TNTs) are membranous structures that enable direct intercellular transfer of mitochondria, proteins, RNAs, and signaling molecules, playing key roles in tissue repair, immune coordination, and stress adaptation.
Tengfei Feng +4 more
doaj +2 more sources
Combining sophisticated fast FLIM, confocal microscopy, and STED nanoscopy for live-cell imaging of tunneling nanotubes [PDF]
Here, we proposed an innovative advanced light imaging to reveal the dynamics of tunneling nanotubes (TNTs) that are now considered as a long- and short-distance route for cell-to-cell communication.
Magalie Bénard +8 more
doaj +2 more sources
Role of Tunneling Nanotubes in the Nervous System. [PDF]
Cellular communication and the transfer of information from one cell to another is crucial for cell viability and homeostasis. During the last decade, tunneling nanotubes (TNTs) have attracted scientific attention, not only as a means of direct intercellular communication, but also as a possible system to transport biological cargo between distant ...
Tarasiuk O, Scuteri A.
europepmc +4 more sources
Tunneling Nanotubes Facilitate Intercellular Protein Transfer and Cell Networks Function
The past decade witnessed a huge interest in the communication machinery called tunneling nanotubes (TNTs) which is a novel, contact-dependent type of intercellular protein transfer (IPT).
Laura Turos-Korgul +4 more
doaj +1 more source
Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma. [PDF]
Tunneling nanotubes are long, non-adherent F-actin-based cytoplasmic extensions which connect proximal or distant cells and facilitate intercellular transfer.
Emil Lou +9 more
doaj +1 more source
The discovery of tunnelling nanotubes (TNTs) and their proposed role in long intercellular transport of organelles, bacteria and viruses have led us to examine their potential role during prion spreading. We have recently shown that these membrane bridges can form between neuronal cells, as well as between dendritic cells and primary neurons and that ...
Gousset, Karine, Zurzolo, Chiara
openaire +4 more sources
Lethal effects of mitochondria via microfluidics
Tumor cells can respond to therapeutic agents by morphologic alternations including formation of tunneling nanotubes. Using tomographic microscope, which can detect the internal structure of cells, we found that mitochondria within breast tumor cells ...
Hyueyun Kim +5 more
doaj +1 more source

