Peering into tunneling nanotubes—The path forward [PDF]
The identification of Tunneling Nanotubes (TNTs) and TNT-like structures signified a critical turning point in the field of cell-cell communication. With hypothesized roles in development and disease progression, TNTs' ability to transport biological cargo between distant cells has elevated these structures to a unique and privileged position among ...
Diégo Cordero Cervantes, Chiara Zurzolo
exaly +5 more sources
Tunneling nanotubes provide a new route for bovine viral diarrhea virus spreading [PDF]
IntroductionBovine viral diarrhea virus (BVDV) is one of the major pathogens currently endangering the world's cattle industry. It poses serious difficulties in prevention and treatment because it can infect cattle of all ages and the specific mechanism ...
Jiying Yin +14 more
doaj +2 more sources
Myosin-X Acts Upstream of L-Plastin to Drive Stress-Induced Tunneling Nanotubes [PDF]
Tunneling nanotubes (TNTs) are thin, actin-based intercellular bridges that enable long-range communication during cellular stress; yet the molecular pathway controlling their formation remains unclear.
Ana Ramirez Perez +2 more
doaj +2 more sources
Multifaceted roles of tunneling nanotubes in intercellular communication [PDF]
Cell-to-cell communication and exchange of materials are vital processes in multicellular organisms during cell development, cell repair and cell survival.
Ludovica eMarzo +2 more
doaj +5 more sources
Combining sophisticated fast FLIM, confocal microscopy, and STED nanoscopy for live-cell imaging of tunneling nanotubes [PDF]
Here, we proposed an innovative advanced light imaging to reveal the dynamics of tunneling nanotubes (TNTs) that are now considered as a long- and short-distance route for cell-to-cell communication.
Magalie Bénard +8 more
doaj +2 more sources
Role of Tunneling Nanotubes in the Nervous System. [PDF]
Cellular communication and the transfer of information from one cell to another is crucial for cell viability and homeostasis. During the last decade, tunneling nanotubes (TNTs) have attracted scientific attention, not only as a means of direct intercellular communication, but also as a possible system to transport biological cargo between distant ...
Tarasiuk O, Scuteri A.
europepmc +4 more sources
Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma. [PDF]
Tunneling nanotubes are long, non-adherent F-actin-based cytoplasmic extensions which connect proximal or distant cells and facilitate intercellular transfer.
Emil Lou +9 more
doaj +1 more source
The discovery of tunnelling nanotubes (TNTs) and their proposed role in long intercellular transport of organelles, bacteria and viruses have led us to examine their potential role during prion spreading. We have recently shown that these membrane bridges can form between neuronal cells, as well as between dendritic cells and primary neurons and that ...
Gousset, Karine, Zurzolo, Chiara
openaire +4 more sources
Lethal effects of mitochondria via microfluidics
Tumor cells can respond to therapeutic agents by morphologic alternations including formation of tunneling nanotubes. Using tomographic microscope, which can detect the internal structure of cells, we found that mitochondria within breast tumor cells ...
Hyueyun Kim +5 more
doaj +1 more source
Pathogenic Stress Induces Human Monocyte to Express an Extracellular Web of Tunneling Nanotubes
Actin-based tunneling nanotubes are a means of intercellular communication between remote cells. In the last decade, this type of nanotube was described in a wide variety of cell types and it became widely accepted that communication through these ...
Michal Shahar, Auryan Szalat, Haim Rosen
doaj +1 more source

