Results 111 to 120 of about 102,927 (346)

Gap junctions in the cardiovascular and immune systems

Brazilian Journal of Medical and Biological Research, 2000
Gap junctions are clusters of intercellular channels directly connecting the cytoplasm of adjacent cells. These channels are formed by proteins named connexins and are present in all metazoan organisms where they serve diverse functions ranging from ...
R. Rozental, A.C. Campos-de-Carvalho, D.C. Spray   +2 more
doaj   +1 more source

Gemcitabine intercellular diffusion mediated by gap junctions: new implications for cancer therapy [PDF]

, 2010
Sylvine Carrondo Cottin, Karim Ghani, Pedro O. de Campos‐Lima, Manuel Caruso   +3 more
openalex   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

Naxos Disease [PDF]

, 2005
Since 1995, according to the World Health Organisation’s classification of cardiomyopathies, Naxos disease has been considered as the recessive form of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C).1 It is a stereotype association of
Protonotarios, Nikos, Tsatsopoulou, Adalena   +1 more
core   +2 more sources

Quercetin, the active phenolic component in kiwifruit, prevents hydrogen peroxide-induced inhibition of gap-junction intercellular communication [PDF]

, 2010
Dong Eun Lee, Bong Jik Shin, Haeng Jeon Hur, Jong Hun Kim, Jiyoung Kim, Nam Joo Kang, Dae‐Ok Kim, Chang Yong Lee, Ki Won Lee, Hyong Joo Lee   +9 more
openalex   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Are there gap junctions without connexins or pannexins?

BMC Evolutionary Biology, 2019
Background Gap junctions (GJ) are one of the most common forms of intercellular communication. GJs are assembled from proteins that form channels connecting the cytoplasm of adjacent cells.
Georgy A. Slivko-Koltchik, Victor P. Kuznetsov, Yuri V. Panchin   +2 more
doaj   +1 more source

Tension at intercellular junctions is necessary for accurate orientation of cell division in the epithelium plane. [PDF]

Proc Natl Acad Sci U S A, 2022
Lisica A, Fouchard J, Kelkar M, Wyatt TPJ, Duque J, Ndiaye AB, Bonfanti A, Baum B, Kabla AJ, Charras GT.   +9 more
europepmc   +1 more source

Connexin43 gap junctional intercellular communication inhibits evx1 expression and joint formation in regenerating fins [PDF]

, 2020
Shashwati Bhattacharya, Caitlin Hyland, Matthias M. Falk, M. Kathryn Iovine   +3 more
openalex   +1 more source