Results 171 to 180 of about 221,929 (293)

The Helicobacter pylori infection alters the intercellular junctions on the pancreas of gerbils (Meriones unguiculatus). [PDF]

World J Microbiol Biotechnol
Hurtado-Monzón EG, Valencia-Mayoral P, Silva-Olivares A, Bañuelos C, Velázquez-Guadarrama N, Betanzos A.   +5 more
europepmc   +1 more source

Senescence-related deterioration of intercellular junctions in the peritoneal mesothelium promotes the transmesothelial invasion of ovarian cancer cells. [PDF]

Sci Rep, 2019
Pakuła M, Witucka A, Uruski P, Radziemski A, Moszyński R, Szpurek D, Maksin K, Woźniak A, Sajdak S, Tykarski A, Mikuła-Pietrasik J, Książek K.   +11 more
europepmc   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

NRF2-HIF2α Signaling Attenuates Endothelial Cell Senescence and Maintains Intercellular Junctions in Diabetes. [PDF]

Int J Biol Sci
Shen J, Lai Y, Lu Y, Liu Y, Zhang J, Wu Y, Pan Y, Chen H, Gao Q, Wei Q, Chen Y, Ye J, Lin Y, Liu B, Jiang J, Nan J.   +15 more
europepmc   +1 more source

Salt bridges gate α-catenin activation at intercellular junctions. [PDF]

Mol Biol Cell, 2018
Barrick S, Li J, Kong X, Ray A, Tajkhorshid E, Leckband D.   +5 more
europepmc   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Vitamin D maintains E-cadherin intercellular junctions by downregulating MMP-9 production in human gingival keratinocytes treated by TNF-α. [PDF]

J Periodontal Implant Sci, 2019
Oh C, Kim HJ, Kim HM.
europepmc   +1 more source

Intercellular junctions and tubulobulbar complexes between sertoli cells in primary culture and in vivo

, 2019
Tubulobulbar complexes (TBCs) are actin-rich structures that form at intercellular junctions in the seminiferous epithelium of the mammalian testis. Massive intercellular junctions form at the base of the epithelium where Sertoli cells are connected to ...
Sriram, Aarati
core  

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. [PDF]

Theranostics, 2019
Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, Yan Y, Huang M, Tang H, Deng Y, Huang S, Zhou Z, Zhang L, Zhang L.   +13 more
europepmc   +1 more source