Results 81 to 90 of about 221,929 (293)

Low-resistance spin-dependent tunnel junctions with HfAlOx barriers for high-density recording-head application [PDF]

open access: yes, 2002
Spin-dependent tunnel junctions with the structure (Ta 70 /spl Aring//NiFe 70 /spl Aring//MnIr 80 /spl Aring//CoFe 35 /spl Aring//HfAlO/sub x//CoFe 35 /spl Aring//NiFe 40 /spl Aring//TiW(N) 150 /spl Aring/) were fabricated on top of 600-/spl Aring/-thick
Snoeck, E.   +4 more
core   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

open access: yesAdvanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang   +11 more
wiley   +1 more source

Cell-cell junctions: a target of acoustic overstimulation in the sensory epithelium of the cochlea

open access: yesBMC Neuroscience, 2012
Background Exposure to intense noise causes the excessive movement of the organ of Corti, stretching the organ and compromising sensory cell functions.
Zheng Guiliang, Hu Bo
doaj   +1 more source

Tunneling spectroscopy of magnetic tunnel junctions [PDF]

open access: yes, 2010
Drewello V. Tunneling spectroscopy of magnetic tunnel junctions. Bielefeld (Germany): Bielefeld University; 2010.In this thesis, magnetic tunnel junctions based on MgO barriers have been prepared and investigated.
Drewello, Volker
core  

Optical Detection of Cellular Signals at Material Interfaces

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren   +5 more
wiley   +1 more source

Novel applications of the Josephson Effect: Ferroelectric Characterisation and Capacitively Shunted Grain Boundary Junctions [PDF]

open access: yes, 2005
This thesis describes applications of the ac Josephson effect. Firstly, results are presented from bicrystal grain boundary YBa2Cu3O7-d junctions shunted with a YBa2Cu3O7-d/SrTiO3/Au multilayer external capacitor, to make a junction with a hysteretic ...

core   +2 more sources

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

open access: yesAdvanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu   +5 more
wiley   +1 more source

Actin at cell-cell junctions is composed of two dynamic and functional populations [PDF]

open access: yes, 2005
The ability of epithelial cells to polarize requires cell-cell adhesion mediated by cadherin receptors. During cell-cell contact, the mechanism via which a flat, spread cell shape is changed into a tall, cuboidal epithelial morphology is not known.
Erasmus, J.   +6 more
core  

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

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