Results 111 to 120 of about 877,216 (239)

Architectures numériques parallèles et successives pour la suppression de spurs multiples dans un terminal radio fréquence multi-standard et performances théoriques

, 2013
National audienceLe thème de ce papier concerne la comparaison d'architectures numériques pour l'annulation de plusieurs spurs, pollutions internes qui surviennent dans les terminaux Radio fréquence (RF).
Belvèze, Fabrice, Brossier, Jean-Marc, Gerzaguet, Robin, Ros, Laurent   +3 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Le Modèle d'Empilement Compressible 4-paramètres [PDF]

, 2015
International audience RÉSUMÉ. Une nouvelle version du Modèle d'Empilement Compressible (MEC) (de Larrard et al.), le MEC 4-paramètres, est présenté dans cet article pour prédire la compacité d'empilements binaires denses désordonnés. Lorsque les tailles
Roquier, Gerard
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Research of Underground Electromagnetic Interference Sources and Anti-interference Technology

Gong-kuang zidonghua, 2012
In view of problem that bad electromagnetic environment of coal mine underground causes phenomenon of false alarm and false power off of safety monitoring and control system, the paper analyzed kinds of underground electromagnetic interference sources ...
LIAO Zhi-qiang, CHEN Dong-chun, LIU Shui-wen   +2 more
doaj  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Formation de voie pour la maximisation du débit dans les schémas d’alignement d’interférence

, 2013
National audienceDans ce papier, nous traitons le problème de la maximisation du débit d'un système multi-utilisateurs, utilisant un schéma d'alignement d'interférence sur un canal à interférence, pour des valeurs de rapport signal à bruit finies.
Aissa El Bey, Abdeldjalil, Amis Cavalec, Karine, Fadlallah, Yasser, Pyndiah, Ramesh   +3 more
core   +1 more source