Results 91 to 100 of about 877,216 (239)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Interference across time: dissociating short from long temporal interference

open access: yesFrontiers in Psychology
Our ability to identify an object is often impaired by the presence of preceding and/or succeeding task-irrelevant items. Understanding this temporal interference is critical for any theoretical account of interference across time and for minimizing its ...
Ilanit Hochmitz   +4 more
doaj   +1 more source

Topographies of Interference

open access: yesLateral, 2014
'Topographies of Interference' is meant to provoke viewers into thinking about information services’ material presence in the world, and to relocate the vision of large tech companies as primarily urban centers to one that highlights their presence in ...
Jocelyn Monahan, Jeff Curran
doaj   +1 more source

L’interférence concurrentielle dans la communication par prospectus : une étude exploratoire. [PDF]

open access: yes
La présence de plusieurs marques concurrentes au sein d’une même page d’un prospectus est une pratique courante. Cette étude s’interroge sur l’effet négatif de cette pratique sur le rappel de la marque et de l’offre promotionnelle en envisageant l ...
Mimouni, Aîda   +2 more
core  

Différents manomètres pour améliorer la ventilation au masque et ballon [PDF]

open access: yes, 2015
peer reviewedINTRODUCTION Les pressions employées lors de la ventilation au ballon sont difficiles à évaluer et souvent inadéquates. Les ballons disposent d’un connecteur où brancher un manomètre (manom) à ressort ou une ligne vers un manom à cadran ...
EIRAS DA SILVA, Sandra   +4 more
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

R2P et précèdent libyen dans la gestion chinoise de la crise syrienne [PDF]

open access: yes
Congrès AFSP Paris 2013 - Le soulèvement populaire syrien de mars 2011 s’est progressivement transformé en une violente guerre civile. Ce conflit intra-étatique a déjà fait plus de 70 000 mors selon l’ONU et plus de 1,5 millions de réfugiés hors des ...
Bondaz, Antoine
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Conversion Numérique-Analogique sélective d'un signal passe-bande soumis à des interférences [PDF]

open access: yes, 2013
National audienceCet article propose une méthode qui permet une conversion numérique-analogique sélective d’un processus aléatoire passe-bande soumis à des interférences.
Chabert, Marie   +2 more
core   +1 more source

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