Results 101 to 110 of about 6,332,703 (315)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Topological phase transition and robust pseudospin interface states induced by angular perturbation in 2D topological photonic crystals. [PDF]

Sci Rep, 2023
Borges-Silva D, Costa CH, Bezerra CG.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Counterpropagating topological interface states in graphene patchwork structures with regular arrays of nanoholes

, 2018
Topological properties of graphene with nanoholes are theoretically investigated in detail. It is revealed that two types of hole arrangements, honeycomb array and triangular array, give rise to two topologically distinct states.
Kariyado, Toshikaze, Yang, Hongxin, Jiang, Yong-Cheng, Hu, Xiao   +3 more
core   +1 more source

Conjugated topological interface-states in coupled ring resonators. [PDF]

Sci Rep, 2021
Lin YC, Chen BY, Hsueh WJ.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Schottky barrier lowering due to interface states in 2D heterophase devices. [PDF]

Nanoscale Adv, 2021
Jelver L, Stradi D, Stokbro K, Jacobsen KW.   +3 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Number of farms, by states, ..., revised estimates.

, 1957
"SpSy 3 (57)"Title from cover.Mode of access: Internet.Updated by: Number of farms, by ...
United States. Crop Reporting Board.
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source