Results 91 to 100 of about 4,081,044 (379)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Publisher Correction: Charging dynamics of an individual nanopore

open access: yesNature Communications, 2019
The original version of this Article contained an error throughout in which an incorrect symbol was used for the diffusion coefficient: it should be cambria math, italicized, and not bold.
Ran Tivony   +4 more
doaj   +1 more source

Colliding Interfaces in Old and New Diffuse-interface Approximations of Willmore-flow [PDF]

open access: yes, 2013
This paper is concerned with diffuse-interface approximations of the Willmore flow. We first present numerical results of standard diffuse-interface models for colliding one dimensional interfaces.
Esedoglu, Selim   +2 more
core   +2 more sources

Interfacing consciousness

open access: yesFrontiers in Psychology
The current stage of consciousness science has reached an impasse. We blame the physicalist worldview for this and propose a new perspective to make progress on the problems of consciousness. Our perspective is rooted in the theory of conscious agents. We thereby stress the fundamentality of consciousness outside of spacetime, the importance of agency,
Robert Prentner   +2 more
openaire   +3 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Skin-inspired hydrogel–elastomer hybrids with robust interfaces and functional microstructures

open access: yesNature Communications, 2016
Inspired by mammalian skins, soft hybrids integrating the merits of elastomers and hydrogels have potential applications in diverse areas including stretchable and bio-integrated electronics, microfluidics, tissue engineering, soft robotics and ...
Hyunwoo Yuk   +4 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Detection of Capillary-Mediated Energy Fields on a Grain Boundary Groove: Solid–Liquid Interface Perturbations

open access: yesMetals, 2017
Grain boundary grooves are common features on polycrystalline solid–liquid interfaces. Their local microstructure can be closely approximated as a “variational” groove, the theoretical profile for which is analyzed here for its Gibbs–Thomson thermo ...
Martin Glicksman, Kumar Ankit
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Charging dynamics of an individual nanopore

open access: yesNature Communications, 2018
Modern energy-storage technologies are based on porous electrodes that store charge within nanometrically-narrow pores or slits. Here the authors show an approach to probe and measure, for the first time, the charging dynamics within an individual nano ...
Ran Tivony   +4 more
doaj   +1 more source

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