Results 111 to 120 of about 3,810,567 (377)

fNIRS-based brain-computer interfaces: a review

Frontiers in Human Neuroscience, 2015
A brain-computer interface (BCI) is a communication system that allows the use of brain activity to control computers or other external devices. It can, by bypassing the peripheral nervous system, provide a means of communication for people suffering ...
Noman Naseer, K. Hong
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Origin and structure of polar domains in doped molecular crystals

Nature Communications, 2016
Doping can introduce structural distortions in a molecular crystal in the form of polar domains. Here, the authors combine pyroelectric measurements and computation to reveal the molecular structure of such domains in centrosymmetric α-glycine crystals ...
E. Meirzadeh, I. Azuri, Y. Qi, D. Ehre, A. M. Rappe, M. Lahav, L. Kronik, I. Lubomirsky   +7 more
doaj   +1 more source

Asymmetric diffusion at the interfaces in multilayers

, 2009
Nanoscale diffusion at the interfaces in multilayers plays a vital role in controlling their physical properties for a variety of applications. In the present work depth-dependent interdiffusion in a Si/Fe/Si trilayer has been studied with sub-nanometer ...
Ajay Gupta, Dileep Kumar, H. Mehrer, Vaishali Phatak   +3 more
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Multi-Scale Evaluation of the Interphase Zone between the Overlay and Concrete Substrate: Methods and Descriptors

Applied Sciences, 2017
This article presents the problem of examining the interphase zone between the overlay and concrete substrate at different levels of observation. The possibility of applying available modern research methods in order to examine the interphase zone with ...
Łukasz Sadowski
doaj   +1 more source

Double Trace Interfaces

, 2017
We introduce and study renormalization group interfaces between two holographic conformal theories which are related by deformation by a scalar double trace operator.
Melby-Thompson, Charles, Schmidt-Colinet, Cornelius   +1 more
core   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Using AI Methods to Evaluate a Minimal Model for Perception

Open Philosophy, 2019
The relationship between philosophy and research on artificial intelligence (AI) has been difficult since its beginning, with mutual misunderstanding and sometimes even hostility.
Prentner Robert, Fields Chris
doaj   +1 more source