Results 81 to 90 of about 744,029 (294)

Estudio in vitro de la actividad antagonista de aislados del virus de la septicemia hemorrágica viral (VHSV) de distinto origen sobre el sistema del IFN tipo I [PDF]

, 2018
El lenguado senegalés (Solea senegalensis) es susceptible a aislados marinos del virus de la septicemia hemorrágica viral (VHSV); sin embargo, los VHSV patógenos para especies de agua dulce no son virulentos para especies marinas.
Alonso-Sanchez, Maria del Carmen, Bejar-Alvarado, Julia, García-Rosado, Esther, Gémez-Mata, Juan, Álvarez-Torres, Daniel   +4 more
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Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity

Nature Communications, 2020
Autoimmune connective tissue diseases arise in a stepwise fashion from asymptomatic preclinical autoimmunity. Type I interferons have a crucial role in the progression to established autoimmune diseases.
A. Psarras, A. Alase, A. Antanaviciute, I. Carr, Md Yuzaiful Md Yusof, M. Wittmann, P. Emery, G. Tsokos, E. Vital   +8 more
semanticscholar   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

ADMINISTRATION CRITERIA FOR INTERFERON-BASED DRUGS AND ITS INDUCERS IN ACUTE RESPIRATORY INFECTIONS IN CHILDREN

Медицинская иммунология, 2014
. Interferon profile was studied in 412 children and 41 adults with acute respiratory virus infections, as well as in forty-eight healthy children and ninety-nine adults.
E. G. Golovacheva, L. W. Ossidak, E. V. Obrastsova, O. I. Afanasyeva   +3 more
doaj   +1 more source

Nuevos fármacos antivirales de acción directa en una población atendida por una unidad de enfermedades infecciosas. Estudio descriptivo [PDF]

, 2017
La hepatitis C es una enfermedad infecciosa que afecta principalmente al hígado y está causada por un virus RNA de cadena positiva perteneciente a la familia Flaviviridae, género Hepacivirus, del que se conocen 7 genotipos, el último descrito ...
Gutiérrez Vélez, Rebeca
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The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Campaña sanitaria sobre hepatitis C en un tratamiento con heroína [PDF]

, 2008
El Programa de Seguimiento de los pacientes del PEPSA (Programa Experimental de Prescripción de eStupefacientes en Andalucía) es un programa de prescripción y dispensación controlada de opioides (apoyada en la Diacetilmorfina o heroína) dirigido a ...
Caracuel González, Francisco José, Equipo PSP-PEPSA, Martínez Casares, José Ángel, Plaza Andrés, Araceli   +3 more
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Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Revisión del tratamiento farmacológico de la esclerosis múltiple. A propósito de un caso [PDF]

, 2019
La esclerosis múltiple es una enfermedad desmielinizante que afecta al sistema nervioso central (SNC), es decir, se produce la destrucción de la vaina de mielina de las neuronas.
Sánchez Lobón, Irene
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