Pathomics-based machine learning model predicts interferon-gamma expression in head and neck squamous cell carcinoma patients. [PDF]
Yu J +6 more
europepmc +1 more source
The organic nanozyme IR‐IHpd, which has NIR‐PDT and POD‐like activity, is designed for continuous ROS generation. It is co‐encapsulated with CB‐839 and coated with DC membranes to simultaneously target tumors and T cells. Under NIR irradiation, immunogenic cell death is activated. Concurrently, CB‐839 suppresses ammonia‐induced T lymphocyte death (AITD)
Meng Suo +7 more
wiley +1 more source
The early human interferon gamma response to Toxoplasma gondii is driven by Vγ9Vδ2 T-cell sensing of host phosphoantigens and subsequent NK-cell activation. [PDF]
Rodriguez F, Saeij JPJ.
europepmc +1 more source
El papel de los receptores TLR2 y CD14 de macrófagos THP-1 en la infección por M. tuberculosis. [PDF]
Arce Mendoza, Alma Yolanda +4 more
core
Synthesis of Bispecific Conjugates by ADP‐Ribosyl Cyclases
Genetic fusion of a CD38 enzymatic domain to antibody scaffolds allows site‐specific conjugation of small‐molecule ligands. Using this approach, a PSMA ligand DUPA is conjugated with an anti‐human CD3 Fab antibody. The resulting bispecific anti‐CD3‐DUPA conjugate facilitates recruitment and activation of cytotoxic T cells against PSMA‐expressing ...
Sunny H. Kim +8 more
wiley +1 more source
Disseminated Mycobacterium avium complex infection presenting as superior vena cava syndrome in a patient with anti-interferon-gamma autoantibody: a case report. [PDF]
Petsut T +3 more
europepmc +1 more source
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang +14 more
wiley +1 more source
Alternative Splicing as a Modulator of the Interferon-Gamma Pathway. [PDF]
Suri P, Badalov A, Ruggiu M.
europepmc +1 more source
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu +17 more
wiley +1 more source
Improving the diagnostic performance for prior COVID-19 with T-SPOT, an interferon-gamma release assay. [PDF]
Yamamoto M +9 more
europepmc +1 more source

