Results 71 to 80 of about 27,778 (225)
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury
Experimental Physiology, EarlyView.Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley +1 more source
SCREENING FOR HEPATITIS C Response from Hepatitis C Trust, BASL, BIA, BVHG, BSG, and BHIVA to article asking whether widespread screening for hepatitis C is justified [PDF]
, 2015 This is the peer reviewed published version of the following article: Response from Hepatitis C Trust, BASL, BIA, BVHG, BSG, and BHIVA to article asking whether widespread screening for hepatitis C is justified, which has been published in final form at ...
Bhagani, S +6 more
core +1 more source
Liver International Communications, Volume 7, Issue 1, March 2026.ABSTRACT Advances in hepatology—such as noninvasive serum biomarkers (e.g., Fibrosure since 2004), imaging techniques (e.g., MR Elastography since 2009 and FibroScan since 2013), and effective direct‐acting antivirals for the treatment of chronic hepatitis C—have likely influenced liver biopsy practices.
Nazire E. Albayrak +8 more
wiley +1 more source
Annals of Hepatology, 2013 The hepatitis C virus (HCV) genotype is an important predictive outcome parameter for pegylated interferon plus ribavirin therapy. Most published therapeutic trials to date have enrolled mainly patients with HCV genotypes 1, 2 and 3. Limited studies have
Juan José Urquijo +16 more
doaj +1 more source
Effectiveness and tolerability of pegylated interferon alfa-2b in combination with ribavirin for treatment of chronic hepatitis C: the PegIntrust Study [PDF]
, 2010 Background and study aims : Large international clinical trials conducted in the past 5 years rapidly improved the treatment of chronic hepatitis C; however, it is unclear whether the advances seen in clinical trials are being paralleled by similar ...
Adler, M +14 more
core +2 more sources
Pharmacoepidemiology and Drug Safety, Volume 35, Issue 3, March 2026.ABSTRACT Purpose Adverse drug reactions (ADRs) present significant obstacles for healthcare systems, impacting both patient safety and the effectiveness of treatments. Despite this, there is a scarcity of research on ADR reports in Sierra Leone, especially over long periods.
Isatu Jalloh +4 more
wiley +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 2010 A polineuropatia desmielinizante inflamatória cônica possui forte associação com a infecção pelo HIV e HCV. Uma rara associação entre PDIC e o tratamento da hepatite C com interferon peguilado alfa foi descrita recentemente.
Bil Randerson Bassetti +3 more
doaj +1 more source
Journal of Viral Hepatitis, Volume 33, Issue 3, March 2026.ABSTRACT Inequitable access to HCV treatment persists, particularly for rural and marginalised populations. Synchronous telemedicine (TM) could mitigate access barriers, but its comparative effectiveness versus in‐person care is uncertain. We performed a systematic review and meta‐analysis comparing synchronous TM with in‐person care for HCV.
Igor Boechat Silveira +6 more
wiley +1 more source
Role of antiviral therapy in the natural history of hepatitis B virus-related chronic liver disease [PDF]
, 2015 Hepatitis B virus (HBV) infection is a dynamic state of interactions among HBV, hepatocytes, and the host immune system. Natural history studies of chronic hepatitis B (CHB) infection have shown an association between active viral replication and adverse
Farinati, Fabio +5 more
core +1 more source
Advanced Science, Volume 13, Issue 8, 9 February 2026.Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li +7 more
wiley +1 more source