Results 51 to 60 of about 306,084 (179)

Theoretical rationale for the choice of interferon alfa-2b substance to be certified as a reference standard for identification test by peptide mapping

Биопрепараты: Профилактика, диагностика, лечение, 2018
The article provides with the results of theoretical research on justification of the choice of methionine form of recombinant interferon alfa-2b substance to be certified as a reference standard for identification test by peptide mapping. At present non-
O. B. Ustinnikova, O. B. Runova, E. O. Goloschapova, L. V. Korsun   +3 more
doaj  

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Tratamento de pacientes com hepatite viral C crônica: a experiência do pólo de aplicação e monitoramento de medicamentos injetáveis do Hospital Nereu Ramos, de 2005 a 2008 [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmácia.O aumento significativo no número de portadores de hepatite viral C crônica é preocupante.
Rosa, Junior André da
core  

Uso tópico do inteferon alfa-2b para neoplasia escamosa da superficie ocular em um caso de paciente com xeroderma pigmentoso

Revista Brasileira de Oftalmologia
Resumo Relato de um caso clínico de Xeroderma Pigmentoso com carcinoma espinocelular de conjuntiva bilateral que apresentou regressão importante das dimensões tumorais com o uso de Interferon alfa-2b tópico.
Nayara Queiroz Cardoso Pinto, Jhonatan de Paula Araujo Ferreira, Gustavo Jose Arruda Mendes Carneiro, Jailton Vieira Silva, Luanna Biana Costa Bezerra, Natália Ponte Nogueira   +5 more
doaj   +1 more source

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

Allergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud, Lene Heise Garvey, Elizabeth Phillips, Michael Ardern‐Jones, Sevim Bavbek, Patrizia Bonadonna, Jean‐Christoph Caubet, Ana‐Maria Copaescu, Valentina Gueli, Jose Julio Laguna, Ricardo Madrigal‐Burgaleta, Francesca Mori, Vito Sabato, Maria J Torres, Knut Brockow   +14 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

The baseline characteristics and treatment outcome between the patients treated with Pegylated interferon-Alfa-2a and Pegylated interferon-Alfa-2b.

, 2014
The baseline characteristics and treatment outcome between the patients treated with Pegylated interferon-Alfa-2a and Pegylated interferon-Alfa-2b.
Tsung-Hsing Hung (579080), Kuo-Chih Tseng (579081), Chih-Wei Tseng (579076), Shu-Fen Wu (352137), Ching-Chih Lee (113210), Shinn-Jia Tzeng (579078), Ting-Tsung Chang (170605), Yu-Hsi Hsieh (579079), Chi-Yi Chen (579077)   +8 more
core   +1 more source

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia, Lisa Zimmer, Lena Lampe, Dimitra Vlachopoulou, Matthias Totzeck, Tienush Rassaf, Raluca I. Mincu   +6 more
wiley   +1 more source

Management of common autoimmune diseases in patients with myeloproliferative neoplasms treated with pegylated interferon alfa—case report, review of the literature and multidisciplinary clinical practice recommendations

Therapeutic Advances in Hematology
Pegylated interferons alfa are increasingly used in patients with myeloproliferative neoplasms (MPN) due to their potential disease-modifying effect. Ropeginterferon alfa-2b has been approved for patients with polycythemia vera (PV) with no symptomatic ...
Axel Rüfer, Christoph Brand, Andrea de Gottardi, Stefan Fischli, Ralph Melzer, Urs Odermatt, Walter A. Wuillemin, Sacha S. Zeerleder   +7 more
doaj   +1 more source

Oxidative stress and antioxidant defense in patients with chronic hepatitis C patients before and after pegylated interferon alfa-2b plus ribavirin therapy

Journal of Translational Medicine, 2006
Background Oxidative stress could play a role in pathogenesis of hepatitis C virus (HCV) infection. The aim of our study is to determine oxidant/antioxidant status of patients with chronic hepatitis C (CHC), and the effect of pegylated interferon alfa-2b
Aytaç Çetinkaya, Polat Eyigun, Ahmet Aydın, Ali Acar, Levent Görenek, Ayşe Eken, Ahmet Sayal   +6 more
doaj   +1 more source