Results 31 to 40 of about 306,084 (179)

The expirience of IDEAL

open access: yesЖурнал инфектологии, 2014
Combination therapy with pegylated interferon-α and ribavirin is the modern standard of chronic hepatitis C treatment [1-3] in Russian Federation [4]. This particular regimen provides achieving of sustained virological response (SVR) in 42-28% of patient
E. Z. Burnevich
doaj   +1 more source

Safety and efficacy of nilotinib after 10 years of interferon

open access: yesClinical Management Issues, 2015
Here we describe a case of a woman with chronic myeloid leukemia at high risk, according to the Sokal Index. The patient started interferon alfa-2b (IFN) at standard dose obtaining a major molecular response after about four years of treatment.
Filippo Russo
doaj   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

open access: yesAdvanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori   +10 more
wiley   +1 more source

Using Recombinant Interferon Alpha-2b in Pediatric Practice

open access: yesZdorovʹe Rebenka, 2016
Interferon system is a key element of antiviral defense of the child’s body that etiopathogenetically justifies the use of nasal and rectal formulations of recombinant interferon alfa-2b for the prevention and treatment of acute respiratory viral ...
Yu.V. Marushko   +2 more
doaj   +1 more source

Interferon-based therapy decreases risks of hepatocellular carcinoma and complications of cirrhosis in chronic hepatitis C patients. [PDF]

open access: yesPLoS ONE, 2013
Interferon-based therapy (IBT) has been the standard of care for hepatitis C virus (HCV) infection. However, conflicting results exist regarding the effects of IBT on risk of developing hepatocellular carcinoma (HCC) and cirrhosis-associated ...
Ching-Sheng Hsu   +6 more
doaj   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Pegile İnterferon alfa-2b İlişkili Deliryum [PDF]

open access: yes, 2012
Kronik interferonların yan etkileri oldukça sıktır. Kronik viral hepatit B tanısı alan 44 yaşında bayan hastaya pegile interferon alfa-2b 1,5 mcg/kg/hafta subkütan başlandı.
C, Üstün
core   +2 more sources

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

open access: yesBMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning   +10 more
wiley   +1 more source

Vaginal biocenosis in pregnant women with recurrent bacterial vaginosis after treatment with recombinant human interferon alpha-2b

open access: yesАкушерство, гинекология и репродукция, 2019
Introduction. Preventing recurrent bacterial vaginosis (BV) during pregnancy is an important issue in current obstetrics.Aim: to assess the effect of recombinant human interferon alpha-2b on the incidence of recurrent BV during pregnancy and on the ...
A. V. Podgornaya   +1 more
doaj   +1 more source

Treatment of Chronic Hepatitis D with Bulevirtide—A Fight against Two Foes—An Update

open access: yesCells, 2022
HDV infection frequently causes progression to cirrhosis and hepatocellular carcinoma (HCC). In summer 2020, the first potentially effective drug Bulevirtide (BLV) has been approved for the treatment of HDV by the EMA.
Peter Ferenci   +2 more
doaj   +1 more source

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