Results 111 to 120 of about 746,766 (243)

Modulation of indoleamine 2,3-dioxygenase by interferon-gamma in human placental chorionic villi.

open access: yes, 2000
The effect of interferon-gamma on indoleamine 2,3-dioxygenase, a tryptophan catabolizing enzyme, was studied in cultured human placental chorionic villi.
Sargent, Ian   +3 more
core   +1 more source

Alpha/beta and gamma interferons are induced by infection with noncytopathic bovine viral diarrhea virus in vivo [PDF]

open access: yes, 2002
In contrast to the results of previous in vitro studies, experimental infection of calves with noncytopathic bovine viral diarrhea virus (ncpBVDV) was found to induce strong alpha/beta and gamma interferon responses in gnotobiotic animals.
Carr, B V   +6 more
core   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

open access: yesAdvanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu   +14 more
wiley   +1 more source

HLA-B*35-restricted CD8(+)-T-cell epitope in Mycobacterium tuberculosis Rv2903c.

open access: yes, 2002
Few human CD8(+) T-cell epitopes in mycobacterial antigens have been described to date. Here we have identified a novel HLA-B*35-restricted CD8(+) T-cell epitope in Mycobacterium tuberculosis Rv2903c based on a reverse immunogenetics approach.
Lukey, Pauline T   +11 more
core   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

Structural and Functional analysis of Interferon Gamma From Bos taurus by Bioinformatic Tools

open access: yesЖивотновъдни науки, 2020
Interferon gamma is a dimerized soluble cytokine that is the only member of the type II class of interferons. Interferon, IFN gamma plays an important role in generating immunity against viruses and intracellular infections.
Anila Hoda   +3 more
doaj  

Detection of gamma interferon.

open access: yes, 2013
Mean optical density (OD) readings of the gamma interferon ELISA (n = 5 for each point and group).
Konstantin P. Lyashchenko (122645)   +15 more
core   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

open access: yesAdvanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen   +17 more
wiley   +1 more source

Frequency of hypovitaminosis d in patients with uveitis presenting at a tertiary care hospital in a low-middle-income country

open access: yesJournal of the Pakistan Medical Association
Objective: To determine the frequency of hypovitaminosis D in patients with uveitis, and to analyse its association with gender and interferon-gamma release assay status. Method: The retrospective, cross-sectional study was conducted in September 2021
Sehrish Nizar Ali Momin   +4 more
doaj   +1 more source

Interferon-? gene+874T -: A polymorphism is associated with tuberculosis and gamma interferon response

open access: yes, 2007
Interferon-gamma is the most important cytokine in resistance to mycobacterial diseases and common variants of interferon-gamma gene could be related to tuberculosis susceptibility.
Uysal, Gulnar   +6 more
core   +1 more source

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