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Interferon-Gamma Release Assays

Clinics in Laboratory Medicine, 2014
Diagnosis of latent tuberculosis infection (LTBI) should be targeted toward individuals and groups with high risk of progression to active tuberculosis (TB). Low-risk populations should not be screened. Interferon-gamma release assays (IGRAs) perform as well or better than the tuberculin skin test in most targeted populations.
Robert, Belknap, Charles L, Daley
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Interferon gamma release assays: principles and practice

Enfermedades Infecciosas y Microbiología Clínica, 2010
The last decade has witnessed significant advances in mycobacterial genomics and cellular research which have resulted in the development of two new blood tests, the enzyme-linked immunospot assay (ELISpot) (TSPOT.TB, Oxford Immunotec, Oxford, UK) and the enzyme-linked immunosorbent assay (ELISA) (QuantiFERON-TB Gold In-Tube, Cellestis, Carnegie ...
Ajit, Lalvani, Manish, Pareek
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[Interferon-gamma release assays in tuberculosis diagnostics]

Der Internist, 2007
Two years ago, CE certified interferon-gamma release assays (IGRA) were launched on the German market (QuantiFERON-TB Gold In-Tube and T-SPOT-TB). Since this time, a multitude of studies have analysed these assays. Guidelines have been elaborated by national expert committees of England, the USA and Switzerland.
H, Hoffmann, G, Loytved, T, Bodmer
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Role of interferon-gamma release assays in healthcare workers

Journal of Hospital Infection, 2009
The advent of interferon-gamma release assays (IGRAs) provides new options for detection of latent tuberculosis infection (LTBI). This is particularly relevant to healthcare workers (HCWs), who are at higher risk of infection, but who have often also been vaccinated.
J E, Swindells   +3 more
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Interferon-gamma release assays and TB diagnosis

Drug and Therapeutics Bulletin, 2009
Worldwide in 2007, there were an estimated 9.27 million new cases of active tuberculosis (TB) and 1.8 million deaths related to the disease. However, in most people with TB, the infection is 'latent'; the underlying cause, Mycobacterium tuberculosis, remains alive but patients are asymptomatic and non-infectious.
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Usefulness of interferon-gamma release assay in diagnosis of renal tuberculosis

Infectious Diseases, 2014
Correspondence: Professor Zhigang Ji, Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1#, Shuaifuyuan, Dongcheng District, Beijing, 100730, P. R. China. Tel: 86 1069156031. Fax: 86 1069156030.
Weibin, Hou   +3 more
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Interferon-gamma release assays for tuberculosis: current and future applications

Expert Review of Respiratory Medicine, 2013
Interferon-gamma release assays (IGRAs) represent the first new tool to diagnose latent tuberculosis infection for more than 100 years. They have advantages over the traditional tuberculin skin test which has a poor specificity due to false-positive responses in people who are BCG vaccinated as there is a cross-reactivity of proteins present in both ...
Muhunthan, Thillai   +3 more
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Interferon gamma release assays for diagnosing active and latent tuberculosis

Expert Opinion on Medical Diagnostics, 2009
In view of the continuing global epidemic of tuberculosis (TB), adequate diagnosis is crucial for controlling this disease. Two commercial interferon gamma release assays (IGRA) have become available: the QuantiFERON-TB (QFT) and the T-SPOT.TB (TSPOT). They offer an important new tool for detecting both latent and active TB.
Steven Ft, Thijsen, Ailko Wj, Bossink
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Tuberculin skin test versus interferon-gamma release assays

Acta Clinica Belgica, 2014
Dear Editor,We would like to discuss on the publication on ‘Tuberculin skin test versus interferon-gamma release assays.’1 De Keyser et al.
S S, Tin, V, Wiwanitkit
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Screening for Mycobacterium tuberculosis Using an Interferon-Gamma Release Assay

Journal of Public Health Management and Practice, 2012
The Centers for Disease Control and Prevention recommend analyzing characteristics of populations screened for Mycobacterium tuberculosis infection using interferon-gamma release assays (IGRAs).We characterized requests for IGRA analyses submitted to the first laboratory in Washington State that began to offer IGRAs as a tuberculosis screening test. In
Terri, Simpson   +3 more
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