Comparison of two IGRA assays exploring cell-mediated immunity against CMV, BKV, and EBV in kidney transplant patients. [PDF]
Monitoring cellular immune responses (CMIs) appears to be a new biomarker in managing immunocompromised patients, especially kidney transplant recipients.
Truffot A +10 more
europepmc +2 more sources
Challenges of Loss to Follow-up in Tuberculosis Research. [PDF]
In studies evaluating methods for diagnosing tuberculosis (TB), follow-up to verify the presence or absence of active TB is crucial and high dropout rates may significantly affect the validity of the results.
A Bailey +41 more
core +30 more sources
Repeat testing or additional tuberculin skin tests for management of indeterminate results of interferon-gamma release assays: a systematic review and meta-analysis. [PDF]
Background Interferon-gamma release assays (IGRAs) are widely used for detecting latent tuberculosis infection (LTBI). However, these tests can yield indeterminate results, posing challenges for clinical management.
Guo X +12 more
europepmc +2 more sources
Evolution of Interferon-Gamma Release Assay Results and Submillisievert Chest CT Findings among Close Contacts of Active Pulmonary Tuberculosis Patients [PDF]
Background Latent tuberculosis (TB) infection among TB contacts is diagnosed using plain chest radiography and interferon-gamma release assays (IGRAs).
Soonho Yoon +4 more
doaj +1 more source
Background: The coronavirus disease 2019 vaccine induces both antibody and T-cell immune responses and has been proven to be effective in preventing coronavirus disease 2019, including its severe disease form, in healthy individuals. However, the details
Ersan Atahan +4 more
doaj +1 more source
‘TB OR NOT TB?’: The Importance of Appropriate Screening
N/a.
Ana Pereira Lemos +3 more
doaj +1 more source
Interferon-gamma release assay has poor diagnostic accuracy in differentiating intestinal tuberculosis from Crohn’s disease in tuberculosis endemic areas [PDF]
Background/Aims Intestinal tuberculosis (ITB) and Crohn’s disease (CD) frequently present with a diagnostic dilemma because of similar presentation.
Karan Sachdeva +10 more
doaj +1 more source
QuantiFERON-TB Gold PLUS versus QuantiFERON-TB Gold In-Tube test for diagnosing tuberculosis infection [PDF]
Background/Aims QuantiFERON-TB Gold PLUS (QFT-PLUS) was developed as a new version of the interferon-γ (IFN-γ) release assay that contains an extra antigen tube to elicit a CD8+ T-cell response in addition to a CD4+ T-cell response.
Soo Han Kim, Kyung-Wook Jo, Tae Sun Shim
doaj +1 more source
Tuberculosis (TB)-associated uveitis is a common cause of infectious uveitis in the developing world. Diagnosis of TB uveitis remains a challenge. The role of interferon gamma release assays (IGRAs) is uncertain.
M A Rehman Siddiqui +2 more
doaj +1 more source
Boosting effect of IL-7 in interferon gamma release assays to diagnose Mycobacterium tuberculosis infection. [PDF]
BACKGROUND:A quarter of the world's population is estimated to be infected with Myobacterium tuberculosis (Mtb). Infection is detected by immune response to M.
Hellen Hiza +9 more
doaj +1 more source

