MPT64 antigen-induced immune responses as a novel diagnostic tool for tuberculosis [PDF]
Microbiology SpectrumThis study aimed to evaluate novel antigen targets from the region of difference (RD) in Bacillus Calmette–Guérin (BCG) for improving tuberculosis (TB) diagnosis. Seven RD region antigens of Mycobacterium tuberculosis (M.tb) were expressed in Escherichia
Jian Hu +8 more
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Comparison of two IGRA assays exploring cell-mediated immunity against CMV, BKV, and EBV in kidney transplant patients [PDF]
Microbiology SpectrumMonitoring cellular immune responses (CMIs) appears to be a new biomarker in managing immunocompromised patients, especially kidney transplant recipients.
Aurélie Truffot +10 more
doaj +2 more sources
Evolution of Interferon-Gamma Release Assay Results and Submillisievert Chest CT Findings among Close Contacts of Active Pulmonary Tuberculosis Patients [PDF]
Tuberculosis and Respiratory Diseases, 2020 Background Latent tuberculosis (TB) infection among TB contacts is diagnosed using plain chest radiography and interferon-gamma release assays (IGRAs).
Soonho Yoon +4 more
doaj +1 more source
Balkan Medical Journal, 2023 Background: The coronavirus disease 2019 vaccine induces both antibody and T-cell immune responses and has been proven to be effective in preventing coronavirus disease 2019, including its severe disease form, in healthy individuals. However, the details
Ersan Atahan +4 more
doaj +1 more source
‘TB OR NOT TB?’: The Importance of Appropriate Screening
Acta Médica Portuguesa, 2021 N/a.
Ana Pereira Lemos +3 more
doaj +1 more source
QuantiFERON-TB Gold PLUS versus QuantiFERON-TB Gold In-Tube test for diagnosing tuberculosis infection [PDF]
The Korean Journal of Internal Medicine, 2020 Background/Aims QuantiFERON-TB Gold PLUS (QFT-PLUS) was developed as a new version of the interferon-γ (IFN-γ) release assay that contains an extra antigen tube to elicit a CD8+ T-cell response in addition to a CD4+ T-cell response.
Soo Han Kim, Kyung-Wook Jo, Tae Sun Shim
doaj +1 more source
Interferon-gamma release assay has poor diagnostic accuracy in differentiating intestinal tuberculosis from Crohn’s disease in tuberculosis endemic areas [PDF]
Intestinal Research, 2023 Background/Aims Intestinal tuberculosis (ITB) and Crohn’s disease (CD) frequently present with a diagnostic dilemma because of similar presentation.
Karan Sachdeva +10 more
doaj +1 more source
Pulmonology, 2023 Background Latent tuberculosis infection (LTBI) diagnosis in a country with a low tuberculosis burden is complicated. Since the prevalence of LTBI in second generation immigrants has not been well recognized, we conducted a cross-sectional study which ...
D. Shlomi +4 more
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Interferon-gamma release assay as a diagnostic test for tuberculosis-associated uveitis [PDF]
Eye, 2012 To study the use of interferon-gamma release assay (IFN-γ) (IGRAs) as a diagnostic test for tuberculosis (TB)-associated uveitis (TAU).Prospective cohort study.Consecutive new patients (n=162) with clinical ocular signs suggestive of TAU, seen >1 year period at a single tertiary center.All subjects underwent investigations to rule out underlying ...
Ang, M, Wong, W, Ngan, C C L, Chee, S-P
openaire +2 more sources
Boosting effect of IL-7 in interferon gamma release assays to diagnose Mycobacterium tuberculosis infection. [PDF]
PLoS ONE, 2018 BACKGROUND:A quarter of the world's population is estimated to be infected with Myobacterium tuberculosis (Mtb). Infection is detected by immune response to M.
Hellen Hiza +9 more
doaj +1 more source