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Comparison of tuberculin skin test and in-vitro interferon gamma release tests in diagnosis of tuberculosis in children with household tuberculosis contact

European Respiratory Journal, 2014
Introduction: The aim of this study was to compare nonspecific and specific tuberculosis (TB) antigen IL-18 and IL-27 response of peripheral mononuclear cells in BCG vaccinated children who do and do not develop latent TB after household contact with ...
H. Karabacak   +10 more
semanticscholar   +1 more source

Absence of interferon-gamma release assay conversion following tuberculin skin testing

The International Journal of Tuberculosis and Lung Disease, 2011
The tuberculin skin test (TST) has been the established screening method for tuberculosis (TB) for over a century. Interferon-gamma release assays (IGRAs) using Mycobacterium tuberculosis-specific antigens are increasingly used as diagnostic tests for TB.
Ritz, N.   +5 more
openaire   +3 more sources

Comparison of interferon-gamma release assay and tuberculin test for screening in healthcare workers.

Revista portuguesa de pneumologia, 2010
Healthcare workers (HCWs) have an increased risk of tuberculosis (TB). Screening for latent tuberculosis infection and active TB is therefore essential in infection control programs. Tuberculin skin test (TST) and Interferon -gamma Release Assay (IGRA) were used simultaneously in 1686 HCWs between May 2007 and April 2009.
José Torres, Costa   +5 more
openaire   +3 more sources

OPTIMIZING INTERPRETATION OF THE TUBERCULIN TEST USING AN INTERFERON-GAMMA RELEASE ASSAY AS A REFERENCE STANDARD

Pediatric Infectious Disease Journal, 2011
The interferon-gamma release assays have greater specificity than the tuberculin skin test (TST), and at least equal sensitivity. We analyzed the sensitivity and specificity of the TST in immunocompetent children considering QuantiFERON as the referent standard.
Ana, Méndez-Echevarría   +5 more
openaire   +2 more sources

Interferon‐gamma release assays versus tuberculin skin testing in patients with rheumatoid arthritis

International Journal of Rheumatic Diseases, 2013
AbstractObjectiveThe aim of this study was to analyze the results of interferon‐gamma release assays (IGRAs) and tuberculin skin tests (TST) performed to detect latent tuberculosis infection (LTBI) in patients with rheumatoid arthritis (RA).MethodsInterferon‐γ release assays and TST test results were summarized and systematically reviewed.ResultsFour ...
Gwan Gyu, Song   +2 more
openaire   +2 more sources

Contribution of the interferon-gamma release assay to tuberculosis diagnosis in children and adolescents.

The International Journal of Tuberculosis and Lung Disease, 2018
SETTING As conclusive data on the performance of interferon-gamma release assays (IGRAs) in paediatric TB are lacking, many guidelines do not recommend their use for TB diagnosis in this population in Brazil. OBJECTIVE To evaluate the performance of an
M. V. Silveira   +7 more
semanticscholar   +1 more source

An interferon-gamma release assay test performs well in routine screening for tuberculosis.

Danish medical journal, 2015
A positive interferon-gamma release assay (IGRA) is regarded as proof of latent Mycobacterium tuberculosis infection. We conducted an evaluation of the IGRA test "T-SPOT.TB" to test its performance during clinical routine use by analysing the positivity rate and odds, effect of season and sensitivity.Data from T-SPOT.TB testing together with age and ...
Allan Vestergaard, Danielsen   +4 more
openaire   +1 more source

In vitro interferon-gamma release test in patients with drug-induced pemphigus.

The Israel Medical Association journal : IMAJ, 2008
Drug-specific CD8+ TH1 lymphocytes have been found in the peripheral blood and involved skin of patients with drug-induced bullous exanthems.To determine whether the interferon-gamma release test can identify culprit drugs in pemphigus patients.Clinical and laboratory workup for pemphigus was performed in 14 pemphigus vulgaris patients who had been ...
Ilan, Goldberg   +2 more
openaire   +1 more source

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