Results 111 to 120 of about 779,562 (365)
Role of Type I and II Interferons in Colorectal Cancer and Melanoma
Frontiers in Immunology, 2017 Cancer can be considered an aberrant organ with a hierarchical composition of different cell populations. The tumor microenvironment, including the immune cells and related cytokines, is crucial during all the steps of tumor development.
Simone Di Franco +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives This study sought to evaluate proteomic, metabolomic, and immune signatures in the cerebrospinal fluid of individuals with Down Syndrome Regression Disorder (DSRD). Methods A prospective case–control study comparing proteomic, metabolomic, and immune profiles in individuals with DSRD was performed.
Jonathan D. Santoro +12 more
wiley +1 more source
Nature Immunology, 2018 Stimulator of interferon genes (STING) is an endoplasmic reticulum (ER) signaling adaptor that is essential for the type I interferon response to DNA pathogens.
Sonal Srikanth +16 more
semanticscholar +1 more source
Alphavirus Infection: Host Cell Shut-Off and Inhibition of Antiviral Responses
Viruses, 2016 Alphaviruses cause debilitating disease in humans and animals and are transmitted by blood-feeding arthropods, typically mosquitoes. With a traditional focus on two models, Sindbis virus and Semliki Forest virus, alphavirus research has significantly ...
Jelke J. Fros, Gorben P. Pijlman
doaj +1 more source
Interferon to PEG-Interferon: A Review
TAJ: Journal of Teachers Association, 1970 The interferons (IFNs) are group of naturally occurring cytokines that are secreted by cells of mammalian immune system when they are stimulated by viral, bacterial and other antigens. There are number of alpha IFNs available for treatment purposes. The two most commonly used α-2a and α-2b are made by recombinant technology. When interferon Alpha-2a is
Arm Saifuddin Ekram, MA Ahad, MA Alim
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.Abstract Defining the CSF cytokine/chemokine and injury biomarker signature of glial fibrillary acidic protein (GFAP) autoimmunity can inform immunopathogenesis. CSF GFAP‐IgG‐positive samples (N = 98) were tested for 17 cytokines/chemokines, neurofilament light chain (NfL), and GFAP (ELLA, Bio‐Techne).
Yahel Segal +11 more
wiley +1 more source
Relationship of cytokines and cytokine signaling to immunodeficiency disorders in the mouse
Brazilian Journal of Medical and Biological Research, 1998 The contributions of cytokines to the development and progression of disease in a mouse model of retrovirus-induced immunodeficiency (MAIDS) are controversial.
Morawetz R.A. +6 more
doaj
Evaluation of prognostic value of cell adhesion molecules in chronic hepatitis C therapy
Journal of Venomous Animals and Toxins including Tropical Diseases, 2010 The most reliable determination of severity and prognosis in chronic viral hepatitis is the histological staging of the disease, which comprises an invasive procedure and is often not well accepted by patients.
N Abdallah +3 more
doaj +1 more source
Optimal Therapy of Hepatitis C Dynamics and Sampling Based Analysis [PDF]
arXiv, 2011 We examine two models for hepatitis C viral (HCV) dynamics, one for monotherapy with interferon (IFN) and the other for combination therapy with IFN and ribavirin. Optimal therapy for both the models is determined using the steepest gradient method, by defining an objective functional which minimizes the infected hepatocyte levels, virion population ...
arxiv
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective People with multiple sclerosis (pwMS) may require a high level of daily assistance both for indoor and outdoor activities. Usually, relatives or friends provide daily support to MS patients who have lost personal autonomy. Several factors such as disability level and disease duration may affect the burden of care in caregivers of ...
Giuseppe Schirò +9 more
wiley +1 more source