Results 261 to 270 of about 236,667 (309)
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Journal of interferon research, 1989
Some patients treated with interferon (IFN) have developed antibodies (ABs) to that IFN. We examined the incidence of such ABs in hairy cell leukemia (HCL) patients treated with IFN-alpha 2a and IFN-alpha 2b. In the initial enzyme-linked immunosorbent assay (ELISA) assays, the serum samples were tested against their corresponding IFNs.
J B, Bekisz +3 more
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Some patients treated with interferon (IFN) have developed antibodies (ABs) to that IFN. We examined the incidence of such ABs in hairy cell leukemia (HCL) patients treated with IFN-alpha 2a and IFN-alpha 2b. In the initial enzyme-linked immunosorbent assay (ELISA) assays, the serum samples were tested against their corresponding IFNs.
J B, Bekisz +3 more
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Veterinary Immunology and Immunopathology, 1993
As reported by others using polyclonal antisera, natural human and porcine interferons (IFN)-alpha are antigenically related. Using monoclonal antibodies (mAb) in neutralization and ELISA experiments, we found differences in the subtype/antigenic composition between virus-induced porcine and human leukocyte preparations.
G, Karayianni-Vasconcelos +2 more
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As reported by others using polyclonal antisera, natural human and porcine interferons (IFN)-alpha are antigenically related. Using monoclonal antibodies (mAb) in neutralization and ELISA experiments, we found differences in the subtype/antigenic composition between virus-induced porcine and human leukocyte preparations.
G, Karayianni-Vasconcelos +2 more
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Recombinant alpha2 interferon-related cardiomyopathy
The American Journal of Medicine, 1988I nterferons are naturally occurring proteins with antiviral, antitumor, and immune-modulating activities. Three groups of interferons have been identified: alpha interferon, derived from leukocytes; beta interferon, from fibroblasts, and most recently, gamma interferon, which is derived from lymphocytes.
M C, Cohen, M S, Huberman, R W, Nesto
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Cortisol stimulation by recombinant interferon-α2
Journal of Neuroimmunology, 1986Serum cortisol concentrations were determined by radioimmunoassay in cancer patients undergoing experimental therapy with recombinant interferon-alpha 2. Cortisol concentration rose steadily after interferon administration and was significantly different from that on control day at 8 h following intramuscular injection of interferon-alpha 2.
J, Roosth +3 more
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Interferon-Alpha-2-Induced Stimulation of ACTH and Cortisol Secretion in Man
Neuroendocrinology, 2008Short-term effects of interferon-α<sub>2</sub> on plasma concentrations of adrenocorticotrophic hormone (ACTH) and cortisol were measured in man in relation to interferon absorption. Interferon-α<sub>2</sub> was given subcutaneously at a dose of 3 × 106 IU at 17.00 h to 2 female and 5 male patients who suffered from chronic ...
H, Müller +3 more
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Topical interferon alpha 2 beta therapy in the management of conjunctival papilloma
Optometry - Journal of the American Optometric Association, 2007This article describes the differential diagnosis of conjunctival papillomas and reviews the treatment options with a focus on the new topical interferon alpha 2 beta therapy.A 45-year-old white man presented with a red right eye of approximately 6 months' duration.
Laura A, Falco +3 more
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Recombinant alpha-2 interferon gel treatment of recurrent herpes genitalis
Antiviral Research, 1992Topical recombinant alpha-2 interferon treatment of recurrent genital herpes was studied in a randomized, double-blind, placebo controlled clinical trial. Three hundred and eighty-seven patients were treated at eight study centers with either interferon gel or placebo four times daily for four days.
Mark Lebwohl +12 more
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[Immunogenicity of recombinant interferon alpha-2 in therapy].
Bratislavske lekarske listy, 1999Recombinant human (r)IFN-alpha 2 is successfully used in treatment of haematopoietic malignancies, lymphomas and viral hepatitis B and C as well. One of undesired side-effects of rIFN-alpha 2 is its immunogenicity which could decrease therapeutic potential of the drug. Formation of antibodies against rIFN-alpha 2 in man represents a complex process, in
H, Liptakova, P, Kontsek
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Expression of biologically active human interferon alpha 2 in Aloe vera
Transgenic Research, 2012Methods necessary for the successful transformation and regeneration of Aloe vera were developed and used to express the human protein, interferon alpha 2 (IFNα2). IFNα2 is a secreted cytokine that plays a vital role in regulating the cellular response to viral infection.
William, Lowther +3 more
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Current Eye Research, 1987
Forty-five patients with virologically confirmed dendritic keratitis were treated in a randomized, double-blind controlled study with a basic therapy of trifluorothymidine (TFT) eye drops. In addition they received different human recombinant interferon (rHu IFN) eye drops.
R, Sundmacher +4 more
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Forty-five patients with virologically confirmed dendritic keratitis were treated in a randomized, double-blind controlled study with a basic therapy of trifluorothymidine (TFT) eye drops. In addition they received different human recombinant interferon (rHu IFN) eye drops.
R, Sundmacher +4 more
openaire +2 more sources