Results 111 to 120 of about 210,768 (294)
Advanced Science, EarlyView.Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
wiley +1 more source
Педиатрическая фармакология, 2006 Among many medications recommended for the treatment and prevention against flu and other respiratory acute viral infections, inteferons and interferon inducers hold a special place.
M.G. Pozdnyakova +6 more
doaj +2 more sources
SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening
Advanced Science, EarlyView.Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen +20 more
wiley +1 more source
Advanced Science, EarlyView.This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka +4 more
wiley +1 more source
Long-term pegylated interferon-α and its potential in the treatment of melanoma
, 2009 Reinhard Dummer, Joanna ManganaDepartment of Dermatology, University Hospital, Zürich, SwitzerlandAbstract: Conventional interferons including interferon-α (IFN-α) are cytokines used for years in the treatment of solid tumors
Reinhard Dummer, Joanna Mangana
core
, 2014 The NS1 protein of influenza A viruses is the dedicated viral interferon (IFN)-antagonist. Viruses lacking NS1 protein expression cannot multiply in normal cells but are viable in cells deficient in their ability to produce or respond to IFN.
Fernández, Yolanda +28 more
core +1 more source
Advanced Science, EarlyView.A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li +6 more
wiley +1 more source
, 2008 PhDThe aim of the project was to investigate the mechanism by which HCV evades therapeutic IFN treatment. This involved the development of novel testing systems and their application to patient samples.
Jones, Meleri
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Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Of Mice and Men and Cattle: Functions of the Pneumovirus Nonstructural Proteins NS1 and NS2 in Interferon Escape [PDF]
, 2003 Bovine respiratory syncytial virus (BRSV), family Paramyxoviridae, subfamily Pneumovirinae, is a major etiological agent of respiratory tract disease in calves. A peculiarity of pneumoviruses is the presence of two unique nonstructural protein genes, NS1
Bossert, Birgit
core