Results 41 to 50 of about 1,226,213 (336)

The preventive effects of natural adjuvants, G2 and G2F on tracheal responsiveness and serum IL-4 and IFN-γ (th1/th2 balance) in sensitized guinea pigs

Clinics, 2014
OBJECTIVE:The effects of natural adjuvants on lung inflammation and tracheal responsiveness were examined in sensitized guinea pigs.METHODS:The responses of guinea pig tracheal chains and the serum levels of interleukin-4 and interferon-gamma were ...
Mohammad Hossein Boskabady, Ali Neamati, Saleh Mohaghegh Hazrati, Mohammad Reza Khakzad, Shakeeb Hassan Moosavi, Zahra Gholamnezhad   +5 more
doaj   +1 more source

The role of interferon-gamma and interferon-gamma receptor in tuberculosis and nontuberculous mycobacterial infections

International Journal of Mycobacteriology, 2021
Mycobacterium tuberculosis (Mtb) and nontuberculous mycobacteria (NTM) remain the leading causes of lung disease and mortality worldwide. Interferon-gamma (IFN-γ) and its receptor (IFN-γR) play a key role in mediating immunity against Mtb and NTM.
Jalaledin Ghanavi, Poopak Farnia, Parissa Farnia, Ali Akbar Velayati   +3 more
doaj   +1 more source

IFN-γ and IL-10: seric and placental profile during pig gestation Seric and placental cytokines in pig gestation

Anais da Academia Brasileira de Ciências, 2023
Concentration of interferon-gamma and interleukin-10 in maternal serum and in maternal and fetal porcine placental extracts from different gestation periods was determined.
CAROLINA VÉLEZ, MARIÁNGELES CLAUZURE, DELIA WILLIAMSON, MIRTA A. KONCURAT, CLAUDIO BARBEITO   +4 more
doaj   +1 more source

Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma- production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells

Journal of Experimental Medicine, 1993
Natural killer cell stimulatory factor or interleukin 12 (NKSF/IL-12) is a heterodimeric cytokine produced by monocytes/macrophages, B cells, and possibly other accessory cell types primarily in response to bacteria or bacterial products.
A. D’Andrea, M. Aste‐Amezaga, N. Valiante, Xiaojing Ma, M. Kubin, G. Trinchieri   +5 more
semanticscholar   +1 more source

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity

Journal of Experimental Medicine, 1983
Human blood mononuclear leukocytes stimulated with toxoplasma antigen, concanavalin A, mezerein plus lentil lectin, or staphylococcal enterotoxin A secreted a factor (macrophage-activating factor, or MAF) that enhanced the capacity of human macrophages ...
C. Nathan, H. Murray, Imichael E Wlebe, B. Rubin   +3 more
semanticscholar   +1 more source

Molecular mechanisms of IL-18BP regulation in DLD-1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level [PDF]

, 2008
Interleukin (IL)-18, formerly known as interferon (IFN)-γ-inducing factor, is a crucial mediator of host defence and inflammation. Control of IL-18 bioactivity by its endogenous antagonist IL-18 binding protein (IL-18BP) is a major objective of ...
Bachmann, Malte, Mühl, Heiko, Paulukat, Jens, Pfeilschifter, Josef Martin   +3 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Designing of interferon-gamma inducing MHC class-II binders

Biology Direct, 2013
BackgroundThe generation of interferon-gamma (IFN-γ) by MHC class II activated CD4+ T helper cells play a substantial contribution in the control of infections such as caused by Mycobacterium tuberculosis.
Sandeep Kumar Dhanda, Pooja Vir, G. Raghava   +2 more
semanticscholar   +1 more source

Interleukin -2 ( Il-2 ) and Gamma Interferon ( Ifn ? ) of Lymphocyte Culture Supernatant in Iron Deficiency Anemia Patients with Infection [PDF]

, 2010
Iron is an essential nutrient for every living cells because of it role as molecule fortransport of oxygen, as well as DNA synthesis through synthesis of ribonucleotidereductase.
Bakta, I. M. (I), D, A. S. (AAG), Suata, K. (Ketut), Suega, K. (Ketut)   +3 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source